Large New Study Shows No Link Between IVF And Breast Cancer
There's good news for the many women who have asked their fertility specialist over the years whether there's a link between in vitro fertilization (IVF) and an increased risk of breast cancer. Since IVF involves a temporary increase in hormones - five to ten times higher than normal including hormones that can impact the growth of specific types of breast cancer - it's a fair question. Now, results from the largest, most comprehensive study to date just published in JAMA show no population-wide link. This confirms research of the past few years and counters a few small, earlier studies that concluded otherwise. It is confusing. Various studies over the past ten years have also shown no link between breast cancer and IVF but experts remained cautious as women participating in the research who had IVF treatment during the 1980s had not yet reached menopause. For the latest research "The main takeaway is there's no evidence of an increased subsequent risk of breast cancer, at least in the first couple decades," said Dr. Saundra S. Buys, an oncologist at the Huntsman Cancer Institute at the University of Utah, who was not involved in the new study. The issue has been around for a while fueled by earlier studies with differing results. An analysis in 2013 of eight studies concluded tentatively that IVF did "not raise the risk of breast cancer over all." Still, experts worried that looking at larger numbers of women over a much longer period of time could ...
Conclusion: Our case report underlines the importance of active endoscopic surveillance of the remaining colon and rectum in patients with diverting stomas and inflammatory bowel disease in order to detect stenosis. If endoscopic control is not possible due to obliteration, surgical therapy must be discussed due to the risk of developing cancer.Case Rep Gastroenterol 2018;12:143 –146
Conclusions: This study is the first nationwide study presenting an increase in incidence of EP-NEC patients from 196 to 260 cases annually in the Netherlands. We found the best 5 year relative survival to be for EP-NEC patients with local disease located in the bladder, where the worst 5 year relative survival was found in the oesophagus.
Karine A. Al Feghali, Rami A. Ballout, Assem M. Khamis, Elie A. Akl, Fady B. Geara
Mayra A. Carrillo, Anjie Zhen, Scott G. Kitchen
PROSTATE cancer symptoms can be hard to spot, especially in the early stages. As it progresses, signs of the disease can begin to show, and if the cancer grows outside of the prostate, and other symptoms can develop, including three related to sex.
CONCLUSIONS Our results suggest that gastric cancer cells induce the transition of pericytes to CAFs by exosomes-mediated BMP transfer and PI3K/AKT and MEK/ERK pathway activation, and suggest that pericytes may be an important source of CAFs. PMID: 29668670 [PubMed - in process]
CONCLUSIONS This study is the first to provide evidence that propofol-mediated autophagy regulation is an underlying part of the mechanism by which propofol regulates HeLa cells progression. PMID: 29667627 [PubMed - in process]
Conclusion: The developed tunable resonator satisfied our initial requirements for in vivo EPR imaging and may be able to be further improved using the present finite-element and circuit models if any problems arise during future practical applications. Significance: This work may help to promote EPR imaging of tumor-bearing mice in cancer-related studies.
Are menopausal vasomotor symptoms associated with increased risk of obstructive sleep apnea, independent of obesity?Menopause
Women who smoke and those who have been exposed to second hand smoke have more problems getting pregnant and are more likely to reachmenopause at an earlier age than women who never smoked or those who were exposed to the least amount of second hand smoke. A new investigation from Roswell Park Cancer Institute reached these conclusions after researchers analyzed data on nearly 89,000 women in the U.S. Women who reported smoking were 14 percent more likely to have infertility (meaning that they were unable to get pregnant for a year) and 26 percent more likely to reach menopause earlier than women who didn’t smoke. Th...