Cardiometabolic disease in South Asians: a global health concern in an expanding population

Cardiovascular disease (CVD) is one of the main causes of mortality and morbidity worldwide. As an emerging population, South Asians (SAs) bear a disproportionately high burden of CVD relative to underlying classical risk factors, partly attributable to a greater prevalence of insulin resistance and diabetes and distinct genetic and epigenetic influences. While the phenotypic distinctions between SAs and other ethnicities in CVD risk are becoming increasingly clear, the biology of these conditions remains an area of active investigation, with emerging studies involving metabolism, genetic variation and epigenetic modifiers (e.g., extracellular RNA).

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 5, 2016 Category: Nutrition Authors: Avash Das, Bharath Ambale-Venkatesh, Joao A.C. Lima, Jane E. Freedman, Aferdita Spahillari, Ranendra Das, Saumya Das, Ravi V. Shah, Venkatesh L. Murthy Tags: Review Source Type: research