Gabapentin for the hemodynamic response to intubation: systematic review and meta-analysis

ConclusionIt remains unknown whether gabapentin improves clinically relevant outcomes such as death and myocardial infarction since studies failed to report on these. Nevertheless, gabapentin attenuated increases in heart rate and blood pressure following intubation when compared with the control group. Even so, the studies included in this review were at potential risk of bias. Moreover, they did not include high-risk patients or report adverse hemodynamic outcomes. Future studies are required to address these limitations.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research