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Soy may help protect women with PCOS from diabetes, heart disease

(The Endocrine Society) Women who have polycystic ovary syndrome -- a common cause of female infertility -- may be able to improve their metabolic and cardiovascular health by consuming soy isoflavones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology&Metabolism.
Source: EurekAlert! - Social and Behavioral Science - Category: Global & Universal Source Type: news

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Conclusion: The eIF2α polymorphism is associated with islet β-cell function in a Chinese population. PMID: 29675042 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
In conclusion, Buxus sempervirens leaf extract may be helpful in controlling the development of hyperlipidemia as well as atherosclerosis in diabetic animals. PMID: 29669507 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
CONCLUSION: The increased or decreased activity of these two genes as a result of genetic changes and the development of thrombosis are a challenging and contradictory matter, and the study of genetic variability in ADAMTS13 and vWF genes may be helpful in the diagnosis of thrombotic disorders. PMID: 29669506 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
Authors: Cai Y, Wang Y, Zhi F, Xing QC, Chen YZ Abstract Treating type 2 diabetes mellitus (T2DM) using thiazolidinediones and biguanides can present several challenges for patients. Sanggua Drink (SGD) is a commonly used agent in traditional Chinese medicine, and it consists of Folium Mori, Fructus Momordicae Charantiae, Radix Puerariae Lobatae, and Rhizoma Dioscorea. The hypoglycemic effects and mechanisms of SGD extracts on insulin resistance in diabetic rats were investigated. SGD (1.24 g/kg orally) was verified in T2DM rats induced by a high-fat diet and streptozotocin. The results showed that SGD treat...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Li H, Chu S, Zhao H, Liu D, Liu X, Qu X, Chen J, Li Z, Li J Abstract Diabetic osteoporosis (DO) is a complication of diabetes. Zishen Jiangtang Pill (ZJP) is a Chinese herbal product which has been used in clinic to maintain blood glucose level and bone density for decades. However, the evidence about its mechanism on diabetes and osteoporosis is still unknown. The aim of this study is to investigate therapeutic effect of ZJP on DO in streptozotocin- (STZ-) induced rats. Rats were randomly assigned to 4 groups: one control group (CON), one model group (MOD), and two ZJP treatment groups (1.5 and 3.0&thinsp...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in adult women (1). It can't be cured, but thanks to many years of fruitful research and intensive investigation, multiple modalities to help manage the condition throughout a woman's lifetime have emerged. Those of us who have been in practice for more than a decade or two have likely had the experience of managing mothers and daughters with the condition. Many of us have supported our PCOS patients through an adolescence complicated by acne and hair growth, an early adulthood complicated by infertility and irregular menses, and late reproductive age compl...
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
(University of California - San Diego) Women who have polycystic ovary syndrome (PCOS), a common hormone condition that contributes to infertility and metabolic problems, such as diabetes and heart disease, tend to have less diverse gut bacteria than women who do not have the condition, according to researchers at University of California San Diego School of Medicine, in collaboration with colleagues at Poznan University of Medical Sciences in Poland and San Diego State University.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Polycystic ovary syndrome (PCOS) is a highly inheritable complex genetic trait and one of the most prevalent endocrine-metabolic-reproductive disorders of humans, clinically evident in 10% –15% of reproductive-age women. It is the single most common cause of ovulatory infertility in women and of subfertility overall in Western societies. Fundamentally, most patients with PCOS, particularly those with hyperandrogenic phenotypes, also demonstrate underlying metabolic dysfunction and s ubclinical chronic inflammation, leading to insulin resistance and compensatory hyperinsulinemia.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
Authors: Liu K, Motan T, Claman P Abstract OBJECTIVES: To review the etiology, evaluation, and treatment of hirsutism. EVALUATION: A thorough history and physical examination plus selected laboratory evaluations will confirm the diagnosis and direct treatment. TREATMENT: Pharmacologic interventions can suppress ovarian or adrenal androgen production and block androgen receptors in the hair follicle. Hair removal methods and lifestyle modifications may improve or hasten the therapeutic response. OUTCOMES: At least 6 to 9 months of therapy are required to produce improvement in hirsutism. EVIDENCE: Th...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
DiscussionPolycystic ovary syndrome (PCOS) affects 6-8% of reproductive-age women making it the most common endocrinopathy in this age group. There is no consensus on the specific diagnostic criteria for PCOS in adolescents as many of the characteristics overlap with normal adolescent physiology. However, patients should have evidence of hyperandrogenism, oligo- or amenorrhea, and potentially polycystic ovaries. PCOS has a genetic component although a specific gene has not been identified. Incidence of PCOS is 20-40% for a woman with a family history. Hyperandrogenism Androgen levels change during puberty therefore actual ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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