[Evodiamine induces extrinsic and intrinsic apoptosis of ovarian cancer cells via the mitogen-activated protein kinase/phosphatidylinositol-3-kinase/protein kinase B signaling pathways].
CONCLUSION: Evodiamine can inhibit the growth of ovarian cancer cells by G2/M arrest and intrinsic and extrinsic apoptosis. In addition, evodiamine-induced PI3K/Akt, ERK1/2 MAPK, and p38 MAPK signaling may be involved in cell death.
PMID: 27468551 [PubMed - in process]
Source: Journal of Traditional Chinese Medicine - Category: Complementary Medicine Authors: Wei L, Jin X, Cao Z, Li W Tags: J Tradit Chin Med Source Type: research
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