Tracking How HIV Disrupts Immune System Informs Vaccine Development

< p > Contact: Samiha Khanna < br / > Phone: [phone] < br / > Email: < a href= " mailto:[e-mail] " > [e-mail] < /a > < br / > < a href= " https://www.dukemedicine.org " > https://www.dukehealth.org < /a > < /p > < p > EMBARGOED FOR RELEASE until 2 p.m. (ET) on Friday, July 29, 2016 < /p > < p > < span style= " line-height: 1.2em; " > DURHAM, N.C. -- One of the main mysteries confounding development of an HIV vaccine is why some people infected with the virus make the desired antibodies after several years, but a vaccine can ’t seem to induce the same response. < /span > < /p > < p > A research team led by scientists at the < a href= " https://dhvi.duke.edu/ " > Duke Human Vaccine Institute < /a > has been unraveling that mystery, detailing new insights in a study published July 29 in the journal Science Immunology. < /p > < p > Studying 100 HIV-infected people -- half whose immune systems eventually made antibodies capable of broadly neutralizing the virus and half whose immune systems did not -- the researchers found several key immune differences that should help in the development of a how-to manual for an effective vaccine.   < /p > < p > “This work gives us the beginning of an understanding of the immune mechanisms that control development of broadly neutralizing antibodies, which is a major goal of a successful HIV vaccine,” said < a href= " https://medicine.duke.edu/faculty/barton-ford-haynes-md " > Barton F. Haynes < /a > , M...

Source: DukeHealth.org: Duke Health Features - July 29, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news