Menopause 'may mix up exercise reward pathways in the brain'

Conclusion This research uses an animal model of human menopause – surgically removing the ovaries – to see what effect this would have on rats bred to have either high or low exercise capacity.   As oestrogen has been shown to have an effect on dopamine activity in the brain's motivation centre, the researchers expected that ovary removal would have an effect on the rats' activity. However, what was unexpected was that having prior high exercise capacity seemed to give no protection – these rats seemed to decrease their activity much more than rats that had low activity to start with. These findings could be stretched to explain a possible reason why women who've been through natural or induced menopause (such as having their ovaries removed) may feel less motivated to exercise, particularly if they were very active previously – because of changes in dopamine activity in the brain. However, humans are obviously not genetically engineered rats running on a wheel. Animal studies can give a good insight into biological mechanisms that may be similar in humans, but we don't know that things work exactly the same. We also don't know whether these are permanent changes that would persist in the long term, or whether they're only short-term changes around the time of menopause.  Overall, the findings are of interest, but they do not have any preventative or therapeutic implications. Physical activity is recommended at all stages of...
Source: NHS News Feed - Category: Consumer Health News Tags: Lifestyle/exercise Older people Neurology Source Type: news

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Source: MDDI - Category: Medical Devices Authors: Tags: BIOMEDevice San Jose Implants Source Type: news
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Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: depression featured self improvement anxiety bad habits chronic stress Source Type: blogs
Conclusions: Population of women with diagnosed alcohol dependence enter the menopausal stage at the similar age as the population of female non-drinkers. The time of alcohol abuse is an important factor having an impact on both the course of menopause and the dynamics of the perimenopause period, leading to symptom escalation. The population of female alcoholics shows a decrease in sexual activity and the prevalence of sexual disorders.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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Source: Endokrynologia Polska - Category: Endocrinology Authors: Tags: Endokrynol Pol Source Type: research
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Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Review hypnotics insomnia sedative trazodone treatment Source Type: research
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Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Original Article Source Type: research
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