Editorial commentary: Mapping of persistent atrial fibrillation —Can the driver mechanisms be determined in the clinical setting?

Atrial fibrillation (AF) is a progressive disease that commonly advances into persistent and then permanent AF [1]. The longer AF continues, the outcome of any associated therapeutic options becomes less favorable [2]. With the advancement of persistent AF, electrical and structural remodeling occurs and an atrial substrate develops that promotes the propagation of the arrhythmia [3]. As the AF propagates, it becomes more complex and disorganized [4] as other driving sources may have developed beyond the initial triggers.
Source: Trends in Cardiovascular Medicine - Category: Cardiology Authors: Source Type: research