Voriconazole

Voriconazole (VCZ) is a second generation triazole that is an antifungal agent used in human and veterinary medicine to treat systemic fungal infections. Approved by the United States Food and Drug Administration (USFDA) in 2002, it is a synthetic derivative of fluconazole with changes to the chemical structure that resulted in a greater antifungal spectrum when compared to fluconazole.1 In human medicine, VCZ has an enhanced spectrum of activity that includes Candida spp., Aspergillus spp., Cryptococcus spp., dimorphic fungi (e.g., Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum), and filamentous fungi (e.g., Fusarium spp.), but not Zycomycetes.
Source: Journal of Exotic Pet Medicine - Category: Veterinary Research Authors: Source Type: research