Quitting Smoking While Pregnant: What Works

Nicotine patches, Zyban helped 4 out of 5 women, study says
Source: WebMD Health - Category: Consumer Health News Source Type: news

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A patient referred for prenatal diagnostics, after first-trimester ultrasound due to a previous child with Leber congenital amaurosis, was suggestive of a Meckel syndrome-like phenotype. Fetal autopsy confirmed the multiple anomalies, and whole-exome sequencing of the fetal DNA identified a pathogenic variant in theRPGRIP1 gene, previously identified in the elder sibling, and a variant causative of Meckel syndrome 1 in theMKS1gene. Reporting theMKS1 mutation, which was present in heterozygous state in the elder sibling, as a secondary finding would have enabled the parents to be tested for carrier status of the same varian...
Source: Molecular Syndromology - Category: Molecular Biology Source Type: research
Conclusion High caspase-3 and AIF expressions and low Bcl-2 expression were risk factors for term PROM. Caspase-dependent and independent pathways of apoptosis were involved in the mechanism of PROM in term pregnancy.
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion The pHua and the BDua are predictors of adverse neonatal outcome, and UCBGA is a useful tool for screening newborns at risk. Universal UCBGA should be considered for all deliveries, as it is an accurate screening test for neonatal hypoxia.Resumo Objetivo Avaliar se o pH da art éria umbilical (pHua) ≤ 7,00 e o d éficit de bases da artéria umbilical (BDua) ≥ 12,00 mmol/L s ão preditores de desfechos neonatais adversos. Métodos Estudo observacional, longitudinal e retrospectivo, realizado no Serviço de Ginecolocgia e Obstetrícia do Centro Hospitalar Tondela Vis...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Abstract Objective To describe caffeine consumption during pregnancy and its association with low birth weight (LBW) and preterm birth in the birth cohort of Ribeir ão Preto, state of São Paulo, Brazil, in 2010. Methods Cohort study, with descriptive and analytical approach. Data included 7,607 women and their newborns in Ribeirão Preto, state of São Paulo, Brazil. The women answered standardized questionnaires about reproductive health, prenatal care, li fe habits, sociodemographic conditions, and information about coffee intake. The independent variable was high caffeine consumption ( ≥ 300...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion Plasma TIMP-4 levels were not altered at 20 to 25 weeks of gestation, before the manifestation of clinical symptoms; therefore, they are not good predictors of the development of preeclampsia.Resumo Objetivo Avaliar se o n ível de inibidor tecidual de metaloproteinases tipo-4 (TIMP-4, na sigla em inglês) circulante no período entre 20 e 25 semanas de gestação é um preditor de preeclâmpsia. Métodos Foi realizado um estudo caso-controle aninhado em uma coorte de estudo prospectivo em Ribeirão Preto, São Paul o, Brasil. De 1.400 mulheres grá...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
We present the case of a 23-year-old pregnant woman with a history of Langerhans cell histiocytosis of the mandible submitted to surgery and chemotherapy when she was 10 years old, with diagnosis of ITP since then. At 28 weeks of gestation, she presented with petechiae, epistaxis, and gingival bleeding, with a platelet count of 3 x 109/L and positive IgG antiplatelet antibodies test. At a multidisciplinary discussion, it was decided to delay a cesarean section, due to the absence of fetal distress and to the high risk of morbidity for the patient. Many therapies were attempted without success. The IgG produced a slight and...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Abstract Background: Prenatal stress may increase risk of developing cardiovascular disorders in adulthood. The cardiotoxic effects of catecholamines are mediated via prolonged adrenergic receptor stimulation and increased oxidative stress upon their degradation by monoamine oxidase A (MAO-A). Objectives: We investigated long-term effects of prenatal stress on β (1, 2, 3) adrenergic receptors and MAO-A gene expression in the hearts of adult rat offspring. Methods: Pregnant rats were exposed to unpredictable mild stress during the third week of gestation. RNA was isolated from left ventricular apex and base of adult of...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Abstract Background: Prenatal stress may increase risk of developing cardiovascular disorders in adulthood. The cardiotoxic effects of catecholamines are mediated via prolonged adrenergic receptor stimulation and increased oxidative stress upon their degradation by monoamine oxidase A (MAO-A). Objectives: We investigated long-term effects of prenatal stress on β (1, 2, 3) adrenergic receptors and MAO-A gene expression in the hearts of adult rat offspring. Methods: Pregnant rats were exposed to unpredictable mild stress during the third week of gestation. RNA was isolated from left ventricular apex and base of adult of...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
The S.T.D. has gained ground among all women in the U.S., including those who are expecting.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Syphilis Sexually Transmitted Diseases Pregnancy and Childbirth Babies and Infants Bacteria Centers for Disease Control and Prevention Obstetrics & Gynecology (Journal) Source Type: news
ConclusionsMaternal IFAS knowledge was fair and was associated with maternal age, marital status, parity, employment, monthly income, availability of brochures and support from CHWs. Strengthening provision of IFAS learning materials and enhancing CHWs involvement is recommended.
Source: International Journal of Africa Nursing Sciences - Category: African Health Source Type: research
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