Successful treatment for a severe case of fetal lung disorder CPAM

A successful treatment has now been conducted for the fetal lung disorder Congenital Pulmonary Airway Malformattion (CPAM), also known as Congenital Cystic Adenomatoid Malformation (CCAM). By performing a series of prenatal and postnatal treatments, the infant was discharged from the hospital without subsequent complications. This series of treatments potentially provides another option for families with unborn babies with the same disorder.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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The pathophysiology of congenital cystic adenomatoid malformations (CCAM) of the lung remains poorly understood.
Source: Respiratory Research - Category: Respiratory Medicine Authors: Tags: Research Source Type: research
We report the case of a neonate, who presented with increasing respiratory distress and an abnormal chest radiograph, initially assumed as pneumonic changes. A revised diagnosis of CPAM was made after a chest computed tomography (CT) scan. The neonate subsequently had a successful excision of the affected lobe with remarkable clinical improvement. The case highlights the need to utilize superior imaging studies such as CT when plain radiographs are inconclusive.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
Authors: Tam PK PMID: 31416986 [PubMed - in process]
Source: Hong Kong Medical Journal - Category: General Medicine Tags: Hong Kong Med J Source Type: research
This study aimed to evaluate the prognosis of pulmonary sequestration (PS) by measuring congenital cystic adenomatoid malformation volume ratio (CVR) value in fetal congenital PS. The fetal CVR in 49 cases of fetal PS diagnosed by prenatal ultrasound in Xiangyang No. 1 People ’s Hospital from March 2010 to June 2017 were measured, and the clinical outcomes were observed. According to the prenatal ultrasound CVR value, 49 fetuses diagnosed with PS were divided into 2 groups: group 1 with CVR≥1.26, and group 2 with CVR
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - Category: Research Source Type: research
 A Young Adult with Tracheal Bronchus and Congenital Cystic Adenomatoid Malformation. J Assoc Physicians India. 2019 Apr;67(4):74-75 Authors: Garg K, Gupta R, Kumar A, Handa U, Saini V PMID: 31309803 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusions: Surgical resection should be considered in adults with asymptomatic cysts to prevent malignant transformation. For further analysis, histopathological examination of specimen is essential for a proper diagnosis and eventually further postoperative treatment. PMID: 31262240 [PubMed - as supplied by publisher]
Source: Acta Chirurgica Belgica - Category: Surgery Tags: Acta Chir Belg Source Type: research
We describe a case of a large, predominantly microcystic CCAM in a hydropic fetus treated successfully with direct interstitial injection of a sclerosant agent (3% sodium tetradecyl sulfate) at 23+3 weeks gestation, after multiple failed courses of steroids. Elective thoracoscopic right lower lobectomy was performed at 1 year of life and there have been no respiratory or other medical morbidities since. A literature review of fetal lung masses treated with sclerosants antenatally reveals that sclerotherapy may represent a novel treatment option for large hydropic microcystic CCAMs, which are unresponsive to corticosteroids...
Source: Fetal Diagnosis and Therapy - Category: Perinatology & Neonatology Source Type: research
We report for the first time one case of pulmonary glial heterotopia occured in a one-month baby free from any malformation. She has the particularity of being born from monozygotic monochorionic twin pregnancy where her anencephalic exencephalic sister suffered a medical termination of pregnancy. She presented neonatal respiratory distress, which recurred one month later. Chest X-ray revealed bilateral cystic pulmonary lesions mainly located in the right lung. Given the suspicion of congenital cystic adenomatoid malformation (CCAM), she underwent an upper and a lower right lung lobectomy at four months old. The pathologic...
Source: Annales de Pathologie - Category: Pathology Authors: Tags: Ann Pathol Source Type: research
Conclusion: CLO in adults is rare and is associated with a broad spectrum of symptoms. Precise anamnesis and radiological findings confirm the diagnosis. Surgical resection is the treatment of choice in symptomatic patients.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Source Type: research
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