The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke

Reperfusion therapies play an important role in early-period treatment for patients presenting to the emergency department due to stroke. However, the ischemia-reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia-reperfusion injury.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research

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Condition:   Stress Hyperglycemia and Stroke Intervention:   Other: standard protocol for stroke patients Sponsor:   Ain Shams University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Stroke, Ischemic;   Coronary Artery Disease;   Angina Pectoris, Stable;   Diabetic Peripheral Neuropathy Interventions:   Drug: Buqitongluo Granule;   Drug: Buqitongluo Granule Placebo;   Other: Standard care Sponsors:   Dongzhimen Hospital, Beijing;   The Affiliated Hospital of Changchun University of Chinese Medicine;   The Affiliated Hospital of Shandong University of Chinese Medicine;   The Affiliated Hospital of Chengdu University of Chinese Medicine;   The Second Af...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 28 May 2020Source: American Journal of Kidney DiseasesAuthor(s): James B. Wetmore, Charles A. Herzog, Anne Sexter, David T. Gilbertson, Jiannong Liu, Scott E. Kasner
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Conditions:   Stroke, Ischemic;   Coronary Artery Disease;   Angina Pectoris, Stable;   Diabetic Peripheral Neuropathy Interventions:   Drug: Buqitongluo Granule;   Drug: Buqitongluo Granule Placebo;   Other: Standard care Sponsors:   Dongzhimen Hospital, Beijing;   The Affiliated Hospital of Changchun University of Chinese Medicine;   The Affiliated Hospital of Shandong University of Chinese Medicine;   The Affiliated Hospital of Chengdu University of Chinese Medicine;   The Second Af...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Stress Hyperglycemia and Stroke Intervention:   Other: standard protocol for stroke patients Sponsor:   Ain Shams University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: Rise in AIx within one week after ischaemic stroke may be of additional importance in determining better early and late favourable functional outcome. PMID: 32456469 [PubMed - as supplied by publisher]
Source: Blood Pressure - Category: Hematology Tags: Blood Press Source Type: research
The human connectome reflects the agenda for the new era of brain networks.1 The connectome represents the structural and functional layout of brain networks and often is represented as a mathematical grid.2-4 Brain network graphs provide a simplified view of the human brain connectome, using graph theory to abstractly define the brain as a set of anatomical regions (or “nodes”) and structural connections (called “edges”).4,5
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Supplement Source Type: research
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Source: The Journal of Trauma: Injury, Infection, and Critical Care - Category: Orthopaedics Tags: ORIGINAL ARTICLES Source Type: research
Poststroke depression can lead to functional dependence, cognitive impairment and reduced quality of life. The aim of this study was to evaluate the effects of a percutaneous mastoid electrical stimulator (PME...
Source: BMC Neurology - Category: Neurology Authors: Tags: Research article Source Type: research
Cerebral stroke occurs following ischemic and hemorrhagic lesions in the brain. Survival and recovery of stroke patients depend on the severity of the initial injury but also the therapeutic approaches applied...
Source: BMC Neuroscience - Category: Neuroscience Authors: Tags: Research article Source Type: research
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