Influence of moderate maternal nutrition restriction on the fetal baboon metabolome at 0.5 and 0.9 gestation

Moderately reduced maternal nutrient availability during pregnancy has adverse effects on the fetuses' growth and metabolism during and after pregnancy. The aim of this study was to explore effects of maternal nutrition restriction (MNR) on key metabolites of the fetal energy metabolism, particularly amino acids (AA), nonesterified fatty acids (NEFA), acylcarnitines and phospholipids. These effects may reflect mechanisms relating MNR to later adverse outcomes.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - April 13, 2016 Category: Nutrition Authors: C. Hellmuth, O. Uhl, F.F. Kirchberg, U. Harder, W. Peissner, B. Koletzko, P.W. Nathanielsz Source Type: research