Amenable Treatable Severe Pediatric Epilepsies

Vitamin-dependent epilepsies and multiple metabolic epilepsies are amenable to treatment that markedly improves the disease course. Knowledge of these amenably treatable severe pediatric epilepsies allows for early identification, testing, and treatment. These disorders present with various phenotypes, including early onset epileptic encephalopathy (refractory neonatal seizures, early myoclonic encephalopathy, and early infantile epileptic encephalopathy), infantile spasms, or mixed generalized seizure types in infancy, childhood, or even adolescence and adulthood.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research

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Source: Medscape Internal Medicine Headlines - Category: Internal Medicine Tags: Neurology & Neurosurgery News Source Type: news
Publication date: May 2020Source: Epilepsy &Behavior, Volume 106Author(s): Kuo-Liang Chiang, Chin-Yin Huang, Liang-Po Hsieh, Kai-Ping Chang
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
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Source: Behavioural Neurology - Category: Neurology Authors: Tags: Behav Neurol Source Type: research
Abstract Preeclampsia is a dangerous hypertensive disorder of pregnancy with known links to negative child health outcomes. Here, we review epidemiological and basic neuroscience work from the past several decades linking prenatal preeclampsia to altered neurodevelopment. This work demonstrates increased rates of neuropsychiatric disorders [e.g., increased autism spectrum disorder, attention deficit hyperactivity disorder (ADHD)] in children of preeclamptic pregnancies, as well as increased rates of cognitive impairments [e.g., decreased intelligence quotient (IQ), academic performance] and neurological disease (e...
Source: Trends in Neurosciences - Category: Neuroscience Authors: Tags: Trends Neurosci Source Type: research
ConclusionMost patients with temporal lobe epilepsy and CSF GAD65-Abs develop a chronic disease with progressive cognitive impairment and refractory epilepsy regardless of the presence of additional limbic symptoms at onset.
Source: Journal of Neurology - Category: Neurology Source Type: research
The review highlights contemporary views on the problem of suicide in patients with epilepsy. The most relevant theories are presented that describe the emergence of suicidal thoughts and the transition to suicidal attempts. Along with a description of ris...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Publication date: Available online 25 March 2020Source: NeuroImage: ClinicalAuthor(s): Victoria L. Morgan, Catie Chang, Dario J. Englot, Baxter P. Rogers
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Findings may have implications for understanding epilepsy, autism spectrum disorders.
Source: National Institutes of Health (NIH) News Releases - Category: American Health Source Type: news
Condition:   Epilepsy Intractable Interventions:   Procedure: Cathodal Transcranial Direct Current Stimulation;   Procedure: Sham Transcranial direct current stimulation Sponsor:   University of Campinas, Brazil Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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