People-Oriented Jobs May Help Lower Alzheimer's Risk

Title: People-Oriented Jobs May Help Lower Alzheimer's Risk Category: Health News Created: 7/24/2016 12:00:00 AM Last Editorial Review: 7/25/2016 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news

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ALZHEIMER ’S disease is the most common cause of dementia. The symptoms of the progressive disease can seem slight at first. A new study has provided a striking explanation for one early warning sign.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Notice NOT-NS-20-001 from the NIH Guide for Grants and Contracts
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
In this study, Warmack produced crystals, both the normal and kinked types, in 15 of beta amyloid ’s amino acids. She used a modified type of cryo-electron microscopy to analyze the crystals. Cryo-electron microscopy, whose development won its creators the 2017 Nobel Prize in chemistry, enables scientists to see large biomolecules in extraordinary detail. Professor Tamir Gonen pioneered the mo dified microscopy, called microcrystal electron diffraction, which enables scientists to study biomolecules of any size.Eisenberg is UCLA ’s Paul D. Boyer Professor of Molecular Biology and a Howard Hughes Medical Institu...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
MONDAY, Aug. 19, 2019 -- Heat waves can pose a serious risk to people with Alzheimer's disease, so their families should know how to keep them safe, advocates say. Extreme heat is " dangerous for everyone, but especially for someone with Alzheimer's...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
Source: The Scientist - Category: Science Tags: Image of the Day Source Type: news
Maintaining fitness through the practice of regular exercise improves health in old age, slowing the pace of damage to the brain and consequent cognitive decline. While there is largely only correlational data in humans to show a link between exercise and a slower pace of neurodegeneration, many animal studies make it clear that exercise causes an improved trajectory for health in later life. It does not extend overall life span in mice, as is the case for calorie restriction, but is otherwise very effective for an intervention that is essentially free. This beneficial outcome is likely due to a combination of overl...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
ACS Chemical NeuroscienceDOI: 10.1021/acschemneuro.9b00271
Source: ACS Chemical Neuroscience - Category: Neuroscience Authors: Source Type: research
This study aimed to investigate the effect of icariin (referred as ICA) on Alzheimer's disease (AD) model through endoplasmic reticulum (ER) stress pathway.Main methodsNine months male APP/PS1 and wild-type (WT) mice were randomly divided into four groups: APP/PS1 control, APP/PS1 + ICA, WT control and WT + ICA groups. The treated mice were given ICA 60 mg/kg/d and control mice were received the same volume distilled water for consecutive 3 months. The Morris water maze and Novel object recognition were used to detect animals' behavior. Nissl staining was used to observe the neuronal morphology in hippocampus a...
Source: Life Sciences - Category: Biology Source Type: research
iad Fajloun Apitherapy is an alternate therapy that relies on the usage of honeybee products, most importantly bee venom for the treatment of many human diseases. The venom can be introduced into the human body by manual injection or by direct bee stings. Bee venom contains several active molecules such as peptides and enzymes that have advantageous potential in treating inflammation and central nervous system diseases, such as Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis. Moreover, bee venom has shown promising benefits against different types of cancer as well as ant...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
Publication date: Available online 18 August 2019Source: Alzheimer's &DementiaAuthor(s): Binyin Li, Yixi He, Jianfang Ma, Pei Huang, Juanjuan Du, Li Cao, Yan Wang, Qin Xiao, Huidong Tang, Shengdi ChenAbstractObjectiveGut microbiota changes before the onset of Alzheimer's disease (AD) and the alterations could be detected in the stage of mild cognitive impairment (MCI). The findings might offer diagnostic biomarkers before the onset of dementia.BackgroundAD is the most common cause of dementia, and MCI is the predementia state. Recent studies suggest the alterations in the gut microbial communities associated with AD, w...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
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