Caesalmins N-Q, new cassane diterpenes from the seeds of Caesalpinia minax

Publication date: September 2016 Source:Phytochemistry Letters, Volume 17 Author(s): Qing Li, Ying-Na He, Bei Niu, Xin-Guo Wang, Li-Ying Niu, Wei Feng Four new cassane diterpenes, named caesalmins N-Q together with six known compounds (1–10) were isolated from the MeOH extract of seeds of Caesalpinia minax Hance. Their structures were elucidated by extensive spectroscopic methods, including NMR, MS, and HRESIMS data. All the new compounds were evaluated for their antiproliferative activities in vitro against three human cancer cell lines, and they showed weak cytotoxic activity with the IC50 values ranging from 45.4 to 78.1 μM. Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research