Abstract < /h3 > < p class= " a-plus-plus " > Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome caused by mutations of the < em class= " a-plus-plus " > NF1 < /em > gene and resulting dysregulation of the Ras-pathway. In addition to peripheral nerve tumors, affected tissues include the musculoskeletal and cardiovascular system. The immune system has recen..."> Abstract < /h3 > < p class= " a-plus-plus " > Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome caused by mutations of the < em class= " a-plus-plus " > NF1 < /em > gene and resulting dysregulation of the Ras-pathway. In addition to peripheral nerve tumors, affected tissues include the musculoskeletal and cardiovascular system. The immune system has recen..." /> Abstract < /h3 > < p class= " a-plus-plus " > Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome caused by mutations of the < em class= " a-plus-plus " > NF1 < /em > gene and resulting dysregulation of the Ras-pathway. In addition to peripheral nerve tumors, affected tissues include the musculoskeletal and cardiovascular system. The immune system has recen..." />