CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mice
Conclusion
This study demonstrates that MDSCs develop during atherosclerosis and reduce atherosclerosis via suppression of pro-inflammatory immune responses.
Source: Cardiovascular Research - Category: Cardiology Authors: Foks, A. C., Van Puijvelde, G. H. M., Wolbert, J., Kröner, M. J., Frodermann, V., Van Der Heijden, T., Van Santbrink, P. J., Boon, L., Bot, I., Kuiper, J. Tags: Vascular Biology Source Type: research