Generic Crestor Wins Approval, Dealing a Blow to AstraZeneca

The F.D.A. allowed eight generics of the cholesterol-lowering pill to go on the market, a move that should considerably decrease its price.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Crestor (Drug) Drugs (Pharmaceuticals) Generic Brands and Products AstraZeneca PLC Food and Drug Administration Source Type: news

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ConclusionsIn this study, age was the strongest determinant of diabetes. And then type 2 diabetes is mainly attributable to WHR, significantly more so in women than men. Therefore, central obesity probably should be considered as a major strategy for reducing incidence of type 2 diabetes.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
CONCLUSION: Besides preventing a modest negative effect of LSM on IL6 and adiponectin level, the combination of LSM and EPA + DHA supplementation could be probably used to improve the functional capacity of adipose tissue in women with overweight. PMID: 30660136 [PubMed - in process]
Source: Central European Journal of Public Health - Category: International Medicine & Public Health Tags: Cent Eur J Public Health Source Type: research
(Natural News) Avocado lovers are in for a treat. Researchers from Mashhad University of Medical Sciences in Iran found that eating this delicious superfood daily can significantly reduce a person’s risk of metabolic syndrome. Metabolic syndrome is a health condition characterized by elevated blood sugar and cholesterol levels, high blood pressure, and obesity. People who suffer from...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
This study aims to as sess how changes in the phosphorylation status of LXRα affect the H3K27Ac histone modification, a known marker for active regulatory elements in promoters and enhancers, in livers of mice mice that carry a whole-body phosphorylation deficient-version of LXRα (S196A) compared to wild-type (WT), in response to a high fat-high cholesterol diet.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Mus musculus Source Type: research
CONCLUSION: Statins have a mild-to-moderate risk of developing NODM. The dose of statins is an important factor that increases the risk of diabetes in statin users
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
AbstractBackgroundTo study the influence of blood lipid levels on hemorrhagic transformation (HT) and prognosis after acute cerebral infarction (ACI).MethodsPatients with ACI within 72  h of symptoms onset between January 1st, 2015, and December 31st, 2016, were retrospectively analyzed. Patients were divided into group A (without HT) and group B (HT). The outcomes were assessed after 3 months of disease onset using the modified Rankin Scale (mRS). An mRS score of 0–2 points indicated excellent prognosis, and an mRS score of 3–6 points indicated poor prognosis.ResultsA total of 732 patients confor...
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research
ConclusionOur results indicate that ezetimibe-mediated inhibition of dietary OC absorption varies depending on the specific OC, and only the absorption of 5,6 β-epoxy is significantly reduced.
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research
AbstractWe established a rabbit iliac artery restenosis model to explore the impact of Telmisartan on the expression of Connexin43 (Cx43) and neointimal hyperplasia. Thirty New Zealand white rabbits were randomly divided into three groups: control group (n = 10), restenosis group (n = 10), and Telmisartan group (n = 10). The restenosis model was established by high-cholesterol diet combined with double-balloon injury of iliac arteries. In addition, Telmisartan at 5 mg/(kg day) was administered to the rabbits of Telmisartan group on the second day after the second balloon injur...
Source: Heart and Vessels - Category: Cardiology Source Type: research
Statin pretreatment (SP) is associated with improved outcomes in acute ischemic stroke (AIS) patients. Collateral circulation status and final infarct volume (FIV) are independent predictors of functional outcome in AIS.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
Conclusion The index might be a useful tool for assessing the nutritional quality of meals and for monitoring and comparing groups.RESUMO Objetivo Avaliar a validade interna e a confiabilidade do índice de qualidade das principais refeições. Métodos O indicador, Índice de Qualidade de Refeição, inclui dez componentes, com pontuação final que varia de 0 a 100 pontos. Estratégias de avaliação do desempenho do indicador incluíram: avaliação da validade de conteúdo, validade de construto, validade discriminante e con...
Source: Revista de Nutricao - Category: Nutrition Source Type: research
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