Rapid recurrence and poor prognosis with altered levels of & #946;-catenin in 3 cases of head and neck Squamous cell carcinoma patients.

We report 3 cases which had considerably higher levels of & beta;-catenin and had rapid recurrence within 3 months, 6 months and 15 months respectively followed by very poor prognosis and death. We speculate presence of resistant cells and higher levels of & beta;-catenin as one of the important prognostic markers for recurrence and therapeutic resistance.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research