' You want a description of hell?' OxyContin's 12-hour problem - Los Angeles Times

The drugmaker Purdue Pharma launched OxyContin two decades ago with a bold marketing claim: One dose relieves pain for 12 hours, more than twice as long as generic medications. Patients would no longer have to wake up in the middle of the night to take their pills, Purdue told doctors. One OxyContin tablet in the morning and one before bed would provide "smooth and sustained pain control all day and all night. " On the strength of that promise, OxyContin became America 's bestselling painkiller, and Purdue reaped $31 billion in revenue. But OxyContin 's stunning success masked a fundamental problem: The drug wears off hours early in many people, a Los Angeles Times investigation found. OxyContin is a chemical cousin of heroin, and when it doesn 't last, patients can experience excruciating symptoms of withdrawal, including an intense craving for the drug. The problem offers new insight into why so many people have become addicted to OxyContin, one of the most abused pharmaceuticals in U.S. history. The Times investigation, based on thousands of pages of confidential Purdue documents and other records, found that: • Purdue has known about the problem for decades. Even before OxyContin went on the market, clinical trials showed many patients weren 't getting 12 hours of relief. Since the drug 's debut in 1996, the company has been confronted with additional evidence, including complaints from doctors, reports ...
Source: Psychology of Pain - Category: Anesthesiology Source Type: blogs

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With the opioid epidemic now claimingnearly 2000 lives from overdose in the United States each month, the medical profession is increasingly accepting the assessment of noted surgeon and writer Atul Gawande, MD:“We started it.” Specialty societies such as theAmerican Academy of Family Physicians andAmerican College of Physicians are offering tools to reduce the unnecessary use of opioids for pain and the risk of addiction. The Federation of State Medical Boards has releasedguidelines for the treatment of chronic pain, and many state medical boards have adopted their own policies. Physicians are responding. Sinc...
Source: JAMA - Category: General Medicine Source Type: research
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Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Health Care syndicated Source Type: blogs
Deaths from opioid overdoses have increased dramatically over the last decade. In 2017, the latest year for which the U.S. government has statistics on the trend, more than 47,000 Americans died of opioid overdoses. One major factor contributing to the rising number of people who get addicted to opioids and die from overdoses is the increasing number of prescriptions written by doctors to treat pain. Overdose deaths related to such prescriptions increased five times from 1999 to 2017. But according to the latest study looking at opioid prescribing patterns, published in the New England Journal of Medicine, recent efforts t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs Source Type: news
Zach (left) and Bob (right) According to the National Institute on Drug Abuse, more than 70,000 Americans died from drug overdoses in 2017, including illicit drugs and prescription opioids, a two-fold increase in a decade. Opioids include prescription opioids and methadone, heroin, and other synthetic narcotics like fentanyl. Bob Paff has directly suffered the casualties of this epidemic. On January 21 of this year he lost his son Zach to an accidental overdose of fentanyl. A highly sought-after communications expert, business leader, and internationally recognized author, Bob now uses his communications platform to bring ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction General Recovery Stigma Opioid Epidemic Opioids Suicide synthetic fentanyl Source Type: blogs
The cell phone blares out reveille. Your eyes open reluctantly and you realize it’s morning, having only gone to bed four hours earlier because of a late-night party. You creak out of bed to ready yourself for work, arthritic joints hurting much more than usual. A painful day lies ahead even after taking ibuprofen. Does this sound familiar? If it does, you are not alone. Nearly 70% of Americans report getting insufficient sleep on a regular basis, and approximately 20% of Americans suffer from chronic pain. Recently, the intersection between these two conditions has become more apparent. The association between sleep...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Fatigue Pain Management Sleep Source Type: blogs
Conclusions: Our results suggest Medicaid expansion benefited a population with unique needs, and that Medicaid expansion could be a valuable tool in addressing the opioid overdose epidemic.
Source: Medical Care - Category: Health Management Tags: Brief Reports Source Type: research
By COLIN KONSCHAK, FACHE and DAVE LEVIN, MD  Dave Levin Colin Konschak The opioid crisis in the United States is having a devastating impact on individuals, their families, and the health care industry. This multi-part series will focus on the role technology can play in addressing this crisis. Part one of the series proposed a strategic framework for evaluating and pursuing technical solutions. A Framework for Innovation In part one of our series, we declared the opioid crisis an “All Hands-On Deck” moment and made the case that health IT (HIT) has a lot to offer. Given the many different possibilities, h...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Tech Access to care Colin Konschak Dave Levin Divurgent Health IT Sansoro Health Source Type: blogs
LYNN (CBS) – Recent research shows the opioid epidemic can be especially deadly for new mothers. When it comes to finding help, long-term options are not usually available. A unique program in Lynn is giving moms the kind of help they need. Jessica Cardinal found the help she needed at the Johnson Street residential treatment program. The 24-year-old recovering heroin addict is now slowly rebuilding her life. A mother of two, Jessica says her darkest days are unrecognizable. “It ended with me in a car shooting heroin with my kid in the back. And that, to me, was my rock bottom,” she recalled. “There...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Lynn Opioid Addiction opioid crisis Source Type: news
By COLIN KONSCHAK, FACHE and DAVE LEVIN, MD Dave Levin Colin Konschak The opioid crisis in the United States is having a devastating impact on individuals, their families, and the health care industry. This multi-part series will focus on the role technology can play in addressing this crisis. Part one of the series proposed a strategic framework for evaluating and pursuing technical solutions. A Framework for Innovation As noted in part one of our series, we believe the opioid crisis is an “All Hands-On Deck” moment and health IT (HIT) has a lot to offer. Given the many different possibilities, having a method...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Data Tech THCB APIs clinical support Colin Konschak Dave Levin Opioid epidemic Source Type: blogs
The current opioid epidemic is tragically affecting many countries including my own. In Australia, the annual death rate from opioid overdose now exceeds the road toll, as is the case in the USA [1]. In the past, as trauma clinicians, we have comforted ourselves by saying that the problem has little to do with us, it is a social problem, and we are there to “pick up the pieces”, when the consequences of addiction result in hospitalisation. Recent evidence suggests that this is not entirely true and that we may be partly to blame for the problem, fuelling the epidemic with our current clinical approaches to mana...
Source: Injury - Category: Orthopaedics Authors: Tags: Editorial Source Type: research
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