i-Fect transfection kits < /a > continue to be used to optimize delivery < em > in vivo < /em > and into hard to transfect cells like < a href= " http://www.neuromics.com/it..."> i-Fect transfection kits < /a > continue to be used to optimize delivery < em > in vivo < /em > and into hard to transfect cells like < a href= " http://www.neuromics.com/it..." /> i-Fect transfection kits < /a > continue to be used to optimize delivery < em > in vivo < /em > and into hard to transfect cells like < a href= " http://www.neuromics.com/it..." />

i-Fect ™ Delivers you siRNA Payload

Delivering siRNA to Dorsal Root Ganglia to Silence K < sub > V < /sub > Receptors. < br / > < br / > Our < a href= " http://www.neuromics.com/ittrium/visit/A1x66x1y1x85b1x1x9cy1x622fx1x96y1x351dx1x82 " target= " _blank " > i-Fect transfection kits < /a > continue to be used to optimize delivery < em > in vivo < /em > and into hard to transfect cells like < a href= " http://www.neuromics.com/ittrium/visit/A1x66x1y1x85b1x1x9cy1x622bx1x96 " target= " _blank " > primary neurons < /a > . In these 2 latest expamples, researchers use i-Fect to deliver siRNA to K < sub > V < /sub > Receptors in Rat DRGs. Knocking down these receptors enable the study of their role in pain modulation: < a href= " http://www.sciencedirect.com/science/article/pii/S0016508512016113 " target= " _blank " > John H. Winston, Sushil K. Sarna. Developmental Origins of Functional Dyspepsia-Like Gastric Hypersensitivity in Rats. < /a > Gastroenterology. Volume 144, Issue 3, March 2013, Pages 570 –579.e3. dx.doi.org/10.1053/j.gastro.2012.11.001....intrathecal treatment, 2 μg of the appropriate siRNA was mixed (1:5 vol/vol) with i-Fect transfection reagent (Neuromics, Edina, MN); rats received 2 ug siRNA/10 uL/rat/injection... < br / > < br / > < div class= " separator " style= " clear: both; text-align: center; " > < a href= " http://3.bp.blogspot.com/-Mb579Vq40Vo/UUSNRfOQe1I/AAAAAAAABx8/mxhQMcXw-kQ/s1600/Kv1.1-siRNA.jpg " imageanchor= " 1 " style= " margin-left: 1em; margin-right: 1em; " > < img bor...
Source: siRNA and DsiRNA Transfection Efficiency - Category: Neuroscience Tags: Delivering siRNA to the CNS Dorsal root ganglia i-Fect in vivo siRNA intrathecal delivery of siRNA KV Receptors kv1.1 Potassium Channel Subunit Kv9.1 Potassium Channel Subunit Transfection Kits Source Type: news