Radioguided Intraoperative Detection of Ectopic Adrenocorticotropic Hormone-Producing Carcinoid Tumor
Publication date: Available online 19 July 2016 Source:Cirugía Española (English Edition) Author(s): Carlos A. Rombolá, Marta Genovés-Crespo, Luz López-Jiménez, Francisco Martín-Ordoñez, Pablo León-Atance
CONCLUSIONOur data suggest that the prognosis of the tumour seems favourable. Surgical resection is the curative treatment. TACE is a favourable option in unresectable tumours.
Pulmonary carcinoid tumors are an uncommon tumor in the lung, representing
Conclusion.Based on long‐term safety data, telotristat ethyl is well tolerated and has a favorable long‐term safety profile in patients with carcinoid syndrome.Implications for Practice.Carcinoid syndrome can cause persistent diarrhea, even in patients treated with somatostatin analogs. Across five clinical trials in patients with carcinoid syndrome, telotristat ethyl has been well tolerated and efficacious, providing clinicians with a new approach to help control carcinoid syndrome diarrhea, in addition to somatostatin analog therapy. By reducing the stool frequency in patients with carcinoid syndrome whose diarrhea i...
Conclusion.SSAs, alone and in combination, are common treatments for advanced lung NETs. Patients have additional treatment options and relatively long survival compared with patients with other advanced cancers. Treatment pattern assessment following approval of newer treatments is needed.Implications for Practice.Somatostatin analogs (SSAs), cytotoxic chemotherapy, EBRT, liver‐directed therapy, and targeted therapies are common treatments for locally advanced/metastatic (typical/atypical) lung neuroendocrine tumors (NETs). SSAs alone or in combination with other treatment modalities were the most common first‐ and se...
We present an extremely rare case of a 3-year-old child with a primary carcinoid tumour of the prostate. A 3-year-old boy presented with failure to thrive, constipation, recurrent respiratory tract infections and pain in the genital area. His karyotype was normal and cystic fibrosis and coeliac disease were excluded prior to further investigation. An abdominopelvic CT scan revealed a prostatic mass. Transrectal ultrasound-guided prostate biopsy was therefore performed and pathological examination revealed a carcinoid tumour.
Publication date: Available online 7 August 2019Source: The Annals of Thoracic SurgeryAuthor(s): Ellen M.B. P. Reuling, Johannes M.A. Daniels, Chris Dickhoff
PMID: 31400319 [PubMed - as supplied by publisher]
In conclusion, the Finnish biobank infrastructure offers excellent opportunities for tissue-based res earch. However, to be able to develop the biobank operations further, involving more medical knowledge in the sample and data acquisition process is a necessity. Also, when working with tissue samples collected over decades, histological expertise is essential for re-evaluation and re-classification of the samples.
Conclusions: Our results suggest that Klotho might be a positive factor for predicting survival in LCNEC and nodal involvement a negative one. Thus, these two markers may assist in the selection of subjects with unfavourable prognosis and to personalise therapy regimens. PMID: 31360195 [PubMed]
Conditions: Carcinoid Heart Disease; Carcinoid Syndrome; Carcinoid Tumor Intervention: Drug: Lutathera Sponsors: King's College Hospital NHS Trust; Advanced Accelerator Applications Not yet recruiting