Comparison of In Vivo Gene Expression Profiling of RPE/Choroid following Intravitreal Injection of Dexamethasone and Triamcinolone Acetonide.

Conclusions. This in vivo study has elucidated several genes and pathways that are potentially altering the circadian rhythms and several other neurotransmitter pathways in RPE/choroid during intravitreal steroid injections, which likely has consequences in the dysregulation of RPE function and neurodegeneration of the retina. PMID: 27429799 [PubMed]

http://www.ncbi.nlm.nih.gov/pubmed/27429799?dopt=Abstract

Source: Journal of Ophthalmology - July 20, 2016 Category: Opthalmology Tags: J Ophthalmol Source Type: research