Genetics Home Reference: schizophrenia
ConclusionsThe presence of TD is associated with worse HRQoL and social withdrawal. The most severe impact of TD is on physical aspects of patients ’ HRQoL.
The company plans to use the funding to expand its capabilities to identify more conditions incuding schizophrenia and multiple sclerosis.
Programs called assertive community treatment provide the kinds of services offered in psychiatric hospitals, within a home setting.
Women with schizophrenia are only half as likely as women in the general population to receive mammograms, reports ameta-analysis published inPsychiatric Services in Advance.“Lower screening rates could explain why women with schizophrenia and other serious mental illnesses are found to have more advanced breast cancer at time of diagnosis,” wrote Alison Hwong, M.D., Ph.D., and colleagues at the University of California, San Francisco. “Given the high prevalence o f breast cancer and the promising prognosis of breast cancer if detected early, mammography screening is a key first step in improving diagnosi...
AbstractContinuing antipsychotic treatment in patients with schizophrenia under clinical remission remains controversial. Even though the mainstream opinion declares an outweighed balance against medication discontinuation, recent reviews and critiques suggest that some patients may remain symptom free and well functioning after stopping antipsychotics, but few predictors can identify who can try medication discontinuation, whilst no guidelines exist for reducing medication to reach the lowest effective dose safely. Analyzing the findings from studies employing different methodologies, adopting evidence from pharmacodynami...
Translational Psychiatry, Published online: 18 November 2019; doi:10.1038/s41398-019-0643-yMitochondrial deficits in human iPSC-derived neurons from patients with 22q11.2 deletion syndrome and schizophrenia
ConclusionsFirstly, variability in neurocognitive and imaging manifestations of B12 deficiency can limit delineation of other pathologies. Failure to improve following correction of nutritional deficiencies warrants further investigation for an alternate diagnosis. Secondly, re-evaluation of patients with comorbid mental health conditions is important in reaching timely and accurate diagnoses.
Abstract Paliperidone palmitate is a second generation antipsychotic, approved for the treatment of schizophrenia in the form of the long-acting injectable (LAI) products INVEGA SUSTENNA® (once monthly injection) and INVEGA TRINZA® (once every 3 months injection). Paliperidone palmitate dissolves slowly after deep intramuscular injection before being hydrolyzed to paliperidone and absorbed into the systemic circulation. The pharmacokinetic (PK) profile of the INVEGA SUSTENNA® formulation is biphasic, comprised of an initial relatively fast zero-order input, which allows rapid attainment of therapeutic ...