Antibiotic-Resistant Gonorrhea Is A Looming Threat
The Centers for Disease Control and Prevention reported Thursday that Neisseria gonorrhoeae ― that is, the bacteria that causes gonorrhea ― could be developing resistance to our last-line antibiotics that treat it. The CDC’s current gold standard treatment for gonorrhea is a combination of two drugs, azithromycin and ceftriaxone, to ensure that if one drug doesn’t kill the bacteria, the other will finish the job. Now, a rise in antibiotic resistance among these two bacteria since 2014 has experts worried. “History has taught us that this bacteria has the ability to develop resistance to antibiotics, and sometimes it can do it quite quickly,” Dr. Robert Kirkcaldy, a medical epidemiologist in the CDC’s STD prevention division told The Huffington Post. “Our ability to cure people of gonorrhea is going to fade unless we take steps now address growing antibiotic resistance.” That said, the United States has not encountered any cases of gonorrhea that are untreatable so far, and despite rising antibiotic resistance, overall resistance rates for the combination treatments are relatively low: just 2.5 percent for azithromycin and 0.8 percent for ceftriaxone. As it stands, gonorrhea is the second-most common sexually transmitted infection in the United States, with more than 350,000 reported cases of the infection in 2014. And while gonorrhea has traditionally has been easy to cure, if left untreated, it can cause severe rep...
Ming-Horng Tsai, Jen-Fu Hsu, Mei-Yin Lai, Lee-Chung Lin, Shih-Ming Chu, Hsuan-Rong Huang, Ming-Chou Chiang, Ren-Huei Fu, Jang-Jih Lu
[Guardian] Kano State Hisbah Board has discovered 15 women with HIV/AIDS among thousands of screened applicants for mass wedding in Kano. Besides, 23 women tested positive to pregnancy screening.
[Daily Maverick] Measles outbreaks are devastating countries across the globe, linked to a massive drop in vaccination rates. The World Health Organisation has raised the alarm and ranked 'vaccine hesitancy' as one of the top 10 threats to public health everywhere. Is South Africa immune?
Analysis of community where 73% of residents contracted Zika in 2015 offers new clues about epidemicScientists studying the 2015 Zika outbreak in Brazil have discovered that people previously exposed to dengue may have been protected from the virus.Three-quarters of the inhabitants of a favela in the country ’s north-east caught the mosquito-borne Zika virus during the epidemic.The outbreak left more than 3,000 babies across Brazil with microcephaly, a birth defect caused by mothers catching the virus during pregnancy.Continue reading...
Mai Okuyama, Hidetoshi Mezawa, Toshinao Kawai, Mitsuyoshi Urashima
hel Venezuelan equine encephalitis virus (VEEV) is an alphavirus in the family Togaviridae. VEEV is highly infectious in aerosol form and a known bio-warfare agent that can cause severe encephalitis in humans. Periodic outbreaks of VEEV occur predominantly in Central and South America. Increased interest in VEEV has resulted in a more thorough understanding of the pathogenesis of this disease. Inflammation plays a paradoxical role of antiviral response as well as development of lethal encephalitis through an interplay between the host and viral factors that dictate virus replication. VEEV has efficient replication mach...
ConclusionThere are conflicting reports in the literature about the association of hyperhomocysteinemia, B12 deficiency, and cerebral venous thrombosis but some reports point to a significant association. We conclude that further studies with a large sample size are required to analyze the effect of hyperhomocysteinemia and low vitamin B12 on the risk of cerebral venous thrombosis.
Many agencies that offer donated embryos, including most of those supported by federal grants, are affiliated with Christian or anti-abortion rights organizations.
CONCLUSION: CXCR2, ANXA1, and CCR3 as well as olfactory receptor-related genes (proteins) may be used as biomarkers to assess zinc status in mice. PMID: 30770772 [PubMed - in process]
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