Hyperthyroidism: Too Much Of A Good Thing

By: Dr. Alan Christianson When someone you know is living with hypothyroidism, it can be tempting to think that if only the doctor would prescribe an extra helping of thyroid hormone, your friend or loved one would feel so much better and would enjoy life more. And in some cases, an extra helping might be in order. In other cases, not so much. Too much thyroid hormone can actually be dangerous, which is why doctors are loathe to bump the levothyroxin dosage up an extra 25 micrograms or so for one of their patients who's still experiencing hypothyroid symptoms. Tests always come first, and there's a good reason for that. Hyperthyroidism is a condition where the thyroid gland produces too much thyroid hormone. It can also be caused by an overdose of thyroid supplement or by ingesting foods that increase thyroid production or that provoke an autoimmune response. How common is it? While less common than its opposite thyroid condition, hyperthyroidism still afflicts around 2 percent of women and 0.2 percent of men, including 3 to 6 million Americans. (1) Who gets it? According to medical statistics, women are 8 to 10 times more likely than men to be diagnosed with hyperthyroidism. And as many as 15% of known cases occur in patients 60 years old or older. (1) Symptoms The most common symptoms of hyperthyroidism include the following: Nervousness or anxiety, irritability Heart palpitations or irregular heartbeat, rapid heartbeat (tachycardia) Panic/anxiety attacks (4) In...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: Available online 13 December 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Rebecca McMillan, Rachael Sumner, Anna Forsyth, Doug Campbell, Gemma Malpas, Elizabeth Maxwell, Carolyn Deng, John Hay, Rhys Ponton, Frederick Sundram, Suresh MuthukumaraswamyAbstractA single subanaesthetic dose of ketamine rapidly alleviates the symptoms of major depressive disorder (MDD). However, few studies have investigated the acute effects of ketamine on the BOLD pharmacological magnetic resonance imaging (phMRI) response and EEG spectra. In a randomised, double-blind, active placebo-co...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
es DU Abstract Human t-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM) is a progressive neurological disease whose diagnosis is defined by clinical manifestations and seropositivity for HTLV-1 infection. Cognitive impairment (CI) is considered to occur after spinal impairment. A 51-year-old HTLV-1-infected man classified as an asymptomatic carrier presented difficulties in listening comprehension and executive memory. He was assessed for central auditory processing (CAP), cognition (event-related auditory evoked potential [P300]), and otoneurological functions (galvanic vestibular-evoked myogen...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
Publication date: Available online 14 December 2019Source: NeuroImageAuthor(s): Daan Christiaens, Jelle Veraart, Lucilio Cordero-Grande, Anthony N. Price, Jana Hutter, Joseph V. Hajnal, J-Donald TournierAbstractProbing microstructure with diffusion magnetic resonance imaging (dMRI) on a scale orders of magnitude below the imaging resolution relies on biophysical modelling of the signal response in the tissue. The vast majority of these biophysical models of diffusion in white matter assume that the measured dMRI signal is the sum of the signals emanating from each of the constituent compartments, each of which exhibits a d...
Source: NeuroImage - Category: Neuroscience Source Type: research
This study aims, first, to validate a retrospectively-gated implementation of the DENSE method for assessing brain tissue pulsations as a physiological marker, and second, to use the acquired measurements to explore intracranial volume dynamics. We acquired repeated measurements of cerebral volumetric strain in 8 healthy subjects, and internally validated these measurements by comparing them to spinal CSF stroke volumes obtained in the same scan session.Peak volumetric strain was found to be highly repeatable between scan sessions. First/second measured peak volumetric strains were: (6.4 ± 1.7)x10−4/(6.7...
Source: NeuroImage - Category: Neuroscience Source Type: research
In this report we conclude normal inflammatory markers cannot be used as exclusion criteria for the disease. We also review the body of literature to summarise the key features of the condition to assist clinicians in its diagnosis.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
We report the case of a falcotentorial meningioma presenting only with binocular, horizontal diplopia in an otherwise healthy sixty-two-year old male. Review of the established literature highlights a lack of consensus regarding management of this extremely rare pineal region tumor. Complete surgical resection ultimately remains the ideal therapeutic option but surgical excision continues to bear serious risk of neurologic and ophthalmic morbidity, including hemianopia and cortical visual impairment. We advocate that a multidisciplinary approach focusing on patient values is critical in treatment of these uncommon lesions....
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 13 December 2019Source: Journal of Clinical NeuroscienceAuthor(s): Shoko Hara, Yoji Tanaka, Yasuhiro Ueda, Daisu Abe, Shihori Hayashi, Motoki Inaji, Taketoshi Maehara, Kenji Ishii, Tadashi NariaiAbstractIt is unclear whether the visual assessment of noninvasive arterial spin labeling magnetic resonance imaging (ASL) can identify instances of hemodynamic compromise including an elevated oxygen extraction fraction (OEF) measured by 15O-gas positron emission tomography (PET). Here we evaluated the relationship between a four-point visual assessment system referred to as 'ASL scores' using AS...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 13 December 2019Source: Prostaglandins, Leukotrienes and Essential Fatty AcidsAuthor(s): Christopher E. Ramsden, Maria Makrides, Zhi-Xin Yuan, Mark S. Horowitz, Daisy Zamora, Lisa N Yelland, Karen Best, Jennifer Jensen, Ameer Y. Taha, Robert A. GibsonAbstractOxidized lipids derived from omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids, collectively known as oxylipins, are bioactive signaling molecules that play diverse roles in human health and disease. Supplementation with n-3 docosahexaenoic acid (DHA) during pregnancy has been reported to decrease the risk of preterm birth i...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) - Category: Lipidology Source Type: research
ConclusionThis study clarifies the differential lipid profiles to distinguish MSPH from MPH and the pathway which is influenced under the condition of MSPH. Also, it provides a resource to look for potential therapeutic targets for MSPH.
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - Category: Lipidology Source Type: research
CONCLUSIONS: AI technologies are growing their role in health care; but, up to now, their "real-life" implementation remains limited. However, in the near future, the potential of AI-driven era could change the clinical practice in Urology, improving overall patient outcomes. PMID: 31833725 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
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