Adventure In Pain

Lots has happened since my last post, and this is a record of those events.  I have to write it somewhere.  It's interesting to me, part of the journey, but you'll be the judge.  It's mostly whining. Background for the reader:  Last Wednesday I had an infusion of a study drug and an infusion of Zometa, and also began a week of oral Valtrex in case my back pain might be the prodrome for shingles.  By Friday the pain in my back and abdomen was much more pronounced, continuing into Saturday.  I posted about that here. Saturday, February 20, 2016: I have a new respect for people who are obliged to tolerate serious, chronic pain.  It consumes me, clouds my mind, makes focus difficult, and I want to lie down and sleep until it goes away.  But sleep is not always possible either.  I can't eat, because nothing sounds good and because it would probably come up again anyway.  To other people I must be a total dud, a zombie, no personality at all except as a whiner. Saturday evening my sweetie took me to the emergency room at a small but very competent local hospital.  Since the pain seemed to be located in the right rear quadrant of my lower abdomen, they did a CT scan there.  They found nothing, sending me home with a prescription for Vicodin (not fillable at that time of Saturday night without a long drive).  Factoid: Vicodin prescriptions can't be faxed in - you have to bring a paper copy to the pharmacy with the d...
Source: Myeloma Hope - Category: Cancer & Oncology Tags: DEX dexamethasone kidney pain Source Type: blogs

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FDA-AACR Workshop to Examine Under-representation of African Americans in Multiple Myeloma Clinical Trials
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
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Source: The Journal of Prosthetic Dentistry - Category: Dentistry Source Type: research
ConclusionsDespite the inherent bias of a retrospective analysis, our long-term results showed a low toxicity profile with a relatively low rate of biochemical control for HT re-treatment in patients affected by local radiorecurrent prostate cancer. Prospective trials are needed to investigate the role of EBRT in this setting.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Publication date: Available online 29 November 2019Source: Practical Radiation OncologyAuthor(s): Robert A. Scranton, Saeed Sadrameli, Edward Brian Butler, Andrew Farach, Hui-Chuan Wang, Bin S. Teh, Ivo W. Tremont-Lukats, Steve H. Fung, Paolo Zanotti-Fregonara, Robert C. RostomilyAbstractStereotactic radiosurgery (SRS) or radiotherapy (SRT) is commonly used to treat brain metastasis (BM). While effective in achieving tumor control, a significant number of BM patients exhibit lesion growth on follow-up MR imaging after SRS which cannot reliably distinguish between tumor growth, radiation necrosis (RN) or a mixture of both. ...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 23 January 2020Source: Physica E: Low-dimensional Systems and NanostructuresAuthor(s): M. Chitra, G. Mangamma, K. Uthayarani, N. Neelakandeswari, E.K. GirijaAbstractIn the present work, individual zinc oxide (ZnO), tin oxide (SnO2) and vanadium oxide (V2O5), their binary and ternary combinations were prepared via hydrothermal route. The structure and the morphology of all the samples were characterised using X-ray Diffractometer (XRD) and Field Emission Scanning Electron Microscopy (FE-SEM) and Raman spectroscopic tools. UV-Visible spectroscopic analysis was recorded for all the samples. ...
Source: Physica E: Low dimensional Systems and Nanostructures - Category: Nanotechnology Source Type: research
Publication date: Available online 22 January 2020Source: Progress in Natural Science: Materials InternationalAuthor(s): Zeyu Bian, Yingtao Liu, Shihan Dai, Zhe Chen, Mingliang Wang, Dong Chen, Haowei WangAbstractMechanical properties of Al–Fe–Ni eutectic alloys have been investigated based on the nominal mass fraction of eutectic phase, and the added Fe/Ni mass ratio. The X-Ray diffraction, scanning electron microscopy equipped with energy dispersive spectroscopy and transmission electron microscope have been used to identify phase composition, characterize microstructure and crystal structure of Al9FeNi phase...
Source: Progress in Natural Science: Materials International - Category: Materials Science Source Type: research
Publication date: Available online 23 January 2020Source: Materials Today: ProceedingsAuthor(s): Kavita A. Deshmukh, Pranjali Khajanji, Swamini Chopra, Abhay Deshmukh, D.R. PeshweAbstractOne of the key requirements in semi-crystalline polyester based polymers is to understand the mechanisms to achieve the level of control on crystallization rate and nucleation efficiency; which is one of the challenges in crystallization kinetics. Thus, in present study the thin films of Thermoplastic Polyurethane (TPU) with addition of micro-graphite were prepared via solution method and significant changes observed in the structural, mec...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
In this study, optimum homogeneous dispersion of multiwall carbon nanotubes (MWCNTs) in titanium oxide were examined using two different dispersion techniques with the aim of determining the milling parameters of the dispersion. The techniques were based on dry milling using high energy ball milling (HEBM) and ultrasonication probe/tip method assisted with HEBM (uHEBM). The HEBM technique was conducted at a milling speed of 100 rpm for 6 and 9 h and uHEBM method was ultrasonicated for 15 min and additional 5 min stirring time using a magnetic stirrer to homogenously mix MWCNT/TiO2 then slurry was milled at same par...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
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Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
This study quantitatively describes the mutual contributions of microporosity and loading conditions (i.e. strain rate and stress amplitude) on the fatigue properties of low-pressure die-cast A356 alloy, in terms of the defect susceptibility coefficient of fatigue life to microporosity variation under various loading conditions. A fatigue test is conducted in high-cycle axial fatigue mode with a variation of strain rate, applying different loading frequencies (0.3–30 Hz) in a stress ratio of R = - 1.0. Computational topography (CT) analysis and scanning-electron microscope (SEM) fractographic observations were ...
Source: Materials Science and Engineering: A - Category: Materials Science Source Type: research
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