What The Fading Ebola Epidemic Can Teach Us About The Looming Zika Crisis

By Thomas Frieden As the world's worst Ebola epidemic fades in the rearview mirror of history, it's worth remembering what happened and the key lessons learned. Beginning in March 2014, Ebola began spreading rapidly in Sierra Leone, Liberia, and Guinea. Nearly 30,000 people were eventually afflicted with the disease, and more than 11,000 died. Ebola spread to Nigeria, Mali, the United States, and other countries. In response to the emerging epidemic, the Centers for Disease Control and Prevention activated its Emergency Operations Center to fight Ebola. This would become the CDC's largest and most intense outbreak response in its 70-year history. The situation was ominous: Ebola was exploding in West Africa, threatening to ignite a global catastrophe. In the following months, more than 4,000 CDC doctors, nurses, laboratory scientists, disease control experts, and others were involved in the response. Nearly half traveled overseas, or to airports, quarantine stations, and hospitals within the United States. For example, laboratory experts set up a mobile lab in Sierra Leone, relocated it as the epidemic shifted, and conducted high-quality, high-throughput testing on more than 27,000 specimens from all over that country for 421 days without interruption. Details of the agency's comprehensive response are documented in a new supplement to the Morbidity and Mortality Weekly Report. Staff not directly involved in the response doubled down on their duties to ensure the ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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In this study, structural proteins of MERS-CoV were expressed in silkworm larvae and Bm5 cells for the development of vaccine candidates against MERS-CoV and diagnostic methods. The spike (S) protein of MERS-CoV lacking its transmembrane and cytoplasmic domains (SοTM) was secreted into the hemolymph of silkworm larvae using a bombyxin signal peptide and purified using affinity chromatography. The purified SοTM forms small nanoparticles as well as the full-length S protein and has the ability to bind human dipeptidyl peptidase 4 (DPP4), which is a receptor of MERS-CoV. These results indicate that bioactive S...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: November 2019Source: Fish &Shellfish Immunology, Volume 94Author(s): Jing Wang, Jia-Jia Du, Biao Jiang, Run-Zhen He, An-Xing LiAbstractShort-term feed deprivation or fasting is commonly experienced by aquaculture fish species and may be caused by seasonal variations, production strategies, or diseases. To assess the effects of fasting on the resistance of Nile tilapia to Streptococcus agalactiae infection, vaccinated and unvaccinated fish were fasted for zero, one, three, and seven days prior to infection. The cortisol levels of both vaccinated and unvaccinated fish first decreased and then increased ...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
ConclusionsThis is the first randomised investigation of BP self-monitoring for the management of pregnancy hypertension and indicates that a large RCT would be feasible.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: Available online 12 October 2019Source: Journal of Hospital InfectionAuthor(s): Jaspreet Dhanda, James Gray, Ellen Knox, Amreen Bashir
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
In the original publication of this article [1], there are error in the Fig.  5, the “ml” should be replaced by “mL” (Fig. 5A) and “IFNγ” should be “IFN-γ” in Fig. 5A, B. The correct figure is below:
Source: Veterinary Research - Category: Veterinary Research Source Type: research
Tubal reversal and pregnancy are possible after endometrial ablation. Dr. Monteith offers hope to women who want to ahve a baby after endometrial ablation. The post Can You Get Pregnant After Endometrial Ablation And Tubal Ligation? appeared first on A Personal Choice.
Source: Tubal Reversal Blog - Category: Reproduction Medicine Authors: Tags: Endometrial Ablation Greencastle Pennsylvania Source Type: blogs
Publication date: Available online 12 October 2019Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Q. Xu, M. Lv, Y. Xia, Y. Zhao, W. Zhang, Y. ChenAbstractA 42-year-old woman presented with a ten-day history of dysphagia, slight chest pain and occasional vomiting. With the performance of thoracic and abdominal enhanced computed tomography (CT) and upper gastrointestinal contrast, once esophageal cancer was suspected. Significant activity mass in esophagus and mediastinal lymph nodes could be found on the imaging of 18F-FDG PET/CT, which also supported malignancy. However, T...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Publication date: Available online 12 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Cristina Miliano, E. Reilly Scott, Laura B. Murdaugh, Emma R. Gnatowski, Christine L. Faunce, Megan S. Anderson, Malissa M. Reyes, Ann M. Gregus, Matthew W. BuczynskiAbstractSmoking tobacco products is the leading cause of preventable death worldwide. Coordinated efforts have successfully reduced tobacco cigarette smoking in the United States; however, electronic cigarettes (e-cigarette) and other electronic nicotine delivery systems (ENDS) recently have replaced traditional cigarettes for many users. While the clinical risk...
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
Publication date: Available online 12 October 2019Source: Veterinary MicrobiologyAuthor(s): Haiyan Sun, Jung-Hyang Sur, Sarah Sillman, David Steffen, Hiep L.X. VuAbstractThe substantial genetic diversity exhibited by influenza A viruses of swine (IAV-S) represents the main challenge for the development of a broadly protective vaccine against this important pathogen. The consensus vaccine immunogen has proven an effective vaccinology approach to overcome the extraordinary genetic diversity of RNA viruses. In this project, we sought to determine if a consensus IAV-S hemagglutinin (HA) immunogen would elicit broad protective ...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
China reported another outbreak of the African swine fever on Sunday in its northwestern province of Gansu, the Ministry of Agriculture and Rural Affairs said on its website.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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