The Root of Alzheimer's: Could Infection and Inflammation be Part of the Equation?

  When it comes to Alzheimer’s disease, a number of researchers think that it’s time to reconsider the idea of infection as a root cause. Scientists are now pointing to studies that reveal the presence of a microbe as a possible trigger for the disease. The theory is that microbes "find their way into the brain via the bloodstream and lie dormant until triggered by aging, immune system decline or by different types of...
Source: Carol Bradley Bursack's SharePosts - Category: Geriatrics Authors: Source Type: blogs

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Source: Jornal Brasileiro de Psiquiatria - Category: Psychiatry Source Type: research
Conclusion Cognitive rehabilitation is able to prolong the independence of the patient in performing activities of daily living and generate functional and structural changes. As a consequence of the finding of few studies that met the eligibility criteria, we also verified the need for more controlled studies and greater application control, considering the high risk of bias in the studies used.
Source: Jornal Brasileiro de Psiquiatria - Category: Psychiatry Source Type: research
Conclusions Nuclear transcription receptors, cerebral cortex and hippocampus, microglia, and amyloid beta protein have shown significant importance in the pathogenesis of Alzheimer ’ s disease in this study.
Source: Jornal Brasileiro de Psiquiatria - Category: Psychiatry Source Type: research
Source: Clinical Interventions in Aging - Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research
Orexins [orexin-A (OXA) and orexin-B (OXB)] are two isoforms of neuropeptides produced by the hypothalamus. The main biological actions of orexins, focused on the central nervous system, are to control the sleep/wake process, appetite and feeding, energy homeostasis, drug addiction, and cognitive processes. These effects are mediated by two G protein-coupled receptor (GPCR) subtypes named OX1R and OX2R. In accordance with the synergic and dynamic relationship between the nervous and immune systems, orexins also have neuroprotective and immuno-regulatory (i.e., anti-inflammatory) properties. The present review gathers recen...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
While Alzheimer’s disease will progress differently for each person, scientists and clinicians have attempted to stage the disease as a way that helps people living with Alzheimer’s and their families understand what is happening, as well as to plan for the future. Some divide AD into seven stages, some five stages, but currently, three stages is the format most often used. The Alzheimer's Association uses three stages, so that is what we will use for our foundation here. Read the full article on HealthCentral to learn more about the stages of Alzheimer's and how knowing them can help you as a caregiver: Carol ...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Diabetes can double a person's chances of developing Alzheimer's. Now researchers are beginning to understand the role of brain metabolism in the development of the disease.(Image credit: Science Source)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news
Condition:   Alzheimer Disease Intervention:   Drug: AAV-hTERT Sponsor:   Libella Gene Therapeutics Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
MONDAY, Oct. 21, 2019 -- Former professional soccer players have a significantly increased risk of death from brain diseases such as Alzheimer's and Parkinson's, a new study finds. Former soccer players were about 3.5 times more likely to die of...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
MONDAY, Oct. 21, 2019 -- Long sleep duration predicts seven-year cognitive decline among U.S. Hispanic/Latino patients, according to a study published online Oct. 9 in Alzheimer's&Dementia. Alberto R. Ramos, M.D., from the University of Miami...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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