Detection of transmissible viral proventriculitis (TVP) and Chicken proventricular necrosis virus (CPNV) in the United Kingdom.

Detection of transmissible viral proventriculitis (TVP) and Chicken proventricular necrosis virus (CPNV) in the United Kingdom. Avian Pathol. 2016 Jul 11;:1-25 Authors: Grau-Roma L, Reid K, de Brot S, Jennison R, Barrow P, Sánchez R, Nofrarías M, Clark M, Majó N Abstract Increasing evidence suggests that a new birnavirus, named Chicken proventricular necrosis virus (CPNV), is the aetiological agent of transmissible viral proventriculitis (TVP). The present work aimed to explore the possible presence of both TVP and CPNV in the UK. Forty-four chickens showing TVP-compatible gross lesions were classified into 3 groups based on the histological lesions: i) TVP-affected chickens: lymphocytic infiltration and glandular necrosis (n=15); ii) lymphocytic proventriculitis (LP)-affected chickens: lymphocytic infiltration without necrosis (n=18); and iii) without proventriculitis (WP): no lymphocytic infiltration or necrosis (n=11). Nine proventriculi (7 out of 15 corresponding to TVP, and 2 out of 11 corresponding to LP) were positive for CPNV by RT-PCR. These results support the previously suggested idea of CPNV as causative agent of TVP. Moreover, this data shows that CPNV can also be detected in a number of cases with LP, which do not fulfil the histological TVP criteria. Phylogenetic analysis of partial sequences of gene VP1 showed that British CPNV sequences were closer to other European CPNV sequences and might constitute a different ...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research