Viability of Lucilia sericata maggots after exposure to wound antiseptics

Abstract After debridement and before dressing a wound with maggots of calliphorid flies, one frequently performed step is the application of antiseptics to the prepared wound bed. However, the concomitant application of antiseptic agents during maggot therapy is regarded controversial as antiseptics may interfere with maggots' viability. In this experimental in vitro study, the viability of fly maggots was investigated after exposure to various antiseptics frequently used in wound care. Here, we show that Lucilia sericata fly maggots can survive up to an hour's exposure to wound antiseptics such as octenidine, povidone‐iodine or polihexanide. Concomitant short‐term application of wound antiseptics together with maggots on wound beds is tolerated by larvae and does not impair their viability.
Source: International Wound Journal - Category: Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Conclusion: Due to the significant antibacterial potency of bacteria-treated larvae secretions, the secretions can be a suitable candidate as a drug against antibiotic resistant bacteria, but additional tests are required. Since the antimicrobial peptides of insects have not yet produced any resistance in human pathogenic bacteria, they can be considered as a promising strategy for dealing with resistant infections. PMID: 30873269 [PubMed]
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
This study was conducted to evaluate the antimicrobial effects of medicinal maggots of Lucilia sericata on Staphylococcus aureus and Pseudomonas aeruginosa on diabetic foot ulcers (DFUs). DESIGN: Randomized controlled trial. SUBJECTS AND SETTING: The sample comprised 50 adult patients from the clinic of the Academic Center for Education, Culture and Research of Tehran University of Medical Sciences, Iran. All participants who had at least 1 DFU present for at least 12 weeks, an arterial brachial index value of more than 0.6, and a hemoglobin A1c value of less than 8% were included in this study. METHODS: Subjects ...
Source: Journal of Wound, Ostomy and Continence Nursing - Category: Nursing Tags: Wound Care Source Type: research
In this study, we quantified the courtship and mating behavior of L. sericata, shedding light on the potential impact of lateralization of selected behavioral traits during sexual interactions. When a male identified a female, he approached her with head pushing followed by foreleg tapping acts. Courtship lasted 7.65 ± 0.4 s. During copulation attempts, the male continued foreleg tapping acts on the female body, and tried to achieve genital contact. Copula lasted 14.88 ± 0.41 min, while male mating success was 85%. Several courtship and mating traits were found latera...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
International Wound Journal, EarlyView.
Source: International Wound Journal - Category: Surgery Authors: Source Type: research
An 8-year-old American Quarter Horse mare presented for acute, traumatic lacerations sustained along the ventral abdomen and hind limbs after an accident involving a manure spreader. A penetrating abdominal wound, extended through the peritoneum, was explored surgically. Peritoneal fluid drained from the abdominal wound for approximately 14 days, which was managed with absorbent bandages and a hernia belt. Wound debridement was augmented with medical maggot therapy initiated on day 11 of hospitalization.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Tags: Case Report Source Type: research
In this study, we quantified the courtship and mating behavior of L. sericata, shedding light on the impact of lateralization of selected behavioral traits during sexual interactions. When a male identified a female, he approached her with head pushing followed by foreleg tapping acts. Courtship lasted 7.65 ± 0.4 s. During copulation attempts, the male continued foreleg tapping acts on the female body, and tried to achieve genital contact. Copula lasted 14.88 ± 0.41 min, while male mating success was 85%. Several courtship and mating traits were found lateralized at p...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
The objective of this work was to bioprospect the salivary glands of Chrysomya megacephala (Fabricius, 1794) larvae, using ultrastructural, morphological, and histological observations, and the total protein electrophoretic profile. The salivary glands present a deferent duct, originating from the buccal cavity, which bifurcates into efferent ducts that insert through a slight dilatation to a pair of tubular-shaped tissues, united in the region of fat cells. Histologically, the secretion had protein characteristics. Cell cytoplasm presented numerous free ribosomes, autophagic vacuoles, spherical and elongated mitochondria,...
Source: Micron - Category: Biology Source Type: research
CONCLUSIONS: More research is needed to determine whether particular dressings or topical agents improve the probability of healing of venous leg ulcers. However, the NMA is uninformative regarding which interventions might best be included in a large trial, largely because of the low certainty of the whole network and of individual comparisons.The results of this NMA focus exclusively on complete healing; whilst this is of key importance to people living with venous leg ulcers, clinicians may wish to take into account other patient-important outcomes and factors such as patient preference and cost. PMID: 29906322 [Pu...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Larval debridement has been historically used in the management of chronic ulcers, but does it still have a place in modern wound healing?Wounds
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
Authors: Raposio E, Bortolini S, Maistrello L, Grasso DA Abstract Cutaneous ulcers tend to become chronic and have a profound impact on quality of life. These wounds may become infected and lead to greater morbidity and even mortality. In the past, larvae (ie, maggots) of certain common flies (Lucilia sericata and Lucilia cuprina) were considered useful in ulcer management because they only remove necrotic tissue while promoting healthy tissue in the wound bed, thus helping wounds heal faster. Recently, maggots from several other fly species (Calliphora vicina, Calliphora vomitoria, Phormia regina, Chrysomya albice...
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
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