Stereotactic Administration of Edaravone Ameliorates Collagenase-Induced Intracerebral Hemorrhage in Rat.

CONCLUSION: SI markedly improved neurological deficits in ICH rat models via antiinflammatory and antiapoptosis mechanisms and promoted M2-type microglia differentiation. SI was effective in rats with collagenase-induced ICH. PMID: 27390192 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27390192?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - July 7, 2016 Category: Neuroscience Authors: Zhang Y, Yang Y, Zhang GZ, Gao M, Ge GZ, Wang QQ, Ji XC, Sun YL, Zhang HT, Xu RX Tags: CNS Neurosci Ther Source Type: research