Ostre uszkodzenie nerek w przebiegu zatrucia metamfetaminą

Publication date: Available online 23 June 2016 Source:Pediatria Polska Author(s): Grażyna Kucharska, Magdalena Filipska, Piotr Adamczyk, Katarzyna Lipiec, Dagmara Roszkowska-Bjanid, Elżbieta Trembecka-Dubel, Maria Szczepańska “Designer drugs”, which act as psychoactive substances, are nowadays applied more often by younger children. They are the mixture of many substances of unknown chemical composition, so it is difficult to predict life-threatening consequences of their use. Currently amphetamine and its derivatives are very popular among the Polish youth. Methamphetamine is one of the fastest and most addictive psychoactive substances. Its use can cause a complex of life-threatening consequences, among them neuroleptic malignant syndrome (including hyperthermia, convulsions and coma), as well as tachycardia, high blood pressure, dehydration, rhabdomyolysis and acute kidney injury. The authors present a case of 17.5-year-old boy who presented with acute kidney injury and other metabolic disorders after consuming the product “crystal” that contained derivatives of methamphetamine. The boy was transferred to the Department of Nephrology in severe general condition with the qualitative and quantitative disorders of consciousness. In laboratory tests hyperglycaemia, metabolic acidosis, increased transaminases and creatinine kinase activity and features of acute renal injury with a significant reduction in glomerular filtration rate (eGFR-13.1ml/min...
Source: Pediatria Polska - Category: Pediatrics Source Type: research