Mechanism proposed for microvascular thrombosis in thrombotic thrombocytopenic purpura

In patients with acquired autoimmune thrombotic thrombocytopenic purpura, elevated plasma levels of human neutrophil proteins 1-3 inhibit proteolytic cleavage of von Willebrand factor by ADAMTS13, Vikram G. Pillai, PhD, of the University of Alabama at Birmingham, and colleagues reported. The...
Source: Skin and Allergy News - Category: Dermatology Source Type: news

Related Links:

Publication date: Available online 9 October 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Sande O. Okelo, Andrew L. Bilderback, Maria Fagnano, Jill S. Halterman
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Vaping product samples from Wisconsin linked to a rash of serious lung injuries tested by U.S. health regulators showed that more than half contained THC, the psychoactive ingredient in marijuana, according to a summary of a preliminary report seen by Reuters.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Public Health & Prevention News Source Type: news
Conclusions: 1. Clinical suspicion of APS requires careful diagnostic testing. Because of inadequate diagnostic workup, many patients may not even have an APS, and these patients could be adequately treated with a DOAC. 2. Patients with single or double positive antiphospholipid antibodies but without positive LA may have a comparably low thrombotic risk and may also be treated with a DOAC in venous TE - sufficient evidence for that conclusion is not yet available but is suggested by the results of meta-analyses. 3. Triple positive patients or those with APS who suffered from arterial thromboembolism have a very high ...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - Category: Surgery Authors: Tags: Vasa Source Type: research
Publication date: Available online 17 October 2019Source: Journal of Molecular BiologyAuthor(s): Alexander Tischer, Maria A. Brehm, Venkata R. Machha, Laurie Moon-Tasson, Linda M. Benson, Katelynn J. Nelton, Rachel R. Leger, Tobias Obser, Marina Martinez-Vargas, Steven T. Whitten, Dong Chen, Rajiv K. Pruthi, H. Robert Bergen, Miguel A. Cruz, Reinhard Schneppenheim, Matthew AutonAbstractVon Willebrand factor (VWF), an exceptionally large multimeric plasma glycoprotein, functions to initiate coagulation by agglutinating platelets in the blood stream to sites of vascular injury. This primary hemostatic function is perturbed i...
Source: Journal of Molecular Biology - Category: Molecular Biology Source Type: research
INTRODUCTION: The level of fear of hymenoptera associated with stinging or envenomation may depend on situational factors and on trait anxiety characteristic of each patient. AIM: To assess the relationship between fear of stinging insects on the o...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Non-Human Animals and Insects Source Type: news
CONCLUSION: Disease progression is an independent predictor with negative impact in overall survival. PMID: 31625877 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
ConclusionsThe PRESERVE Study represents the largest prospective study ever undertaken to investigate real-world outcomes with contemporary use of IVC filters. The investigators await results with the hope that it can improve patient care.
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Conclusions: Recurrent CA-CDI in children in our population is less common than previously reported. This study supports first-line treatment with the standard, short course metronidazole in most cases of primary CA-CDI.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
Conclusions: This is a rare case of sugammadex-induced anaphylaxis that both sugammadex and sugammadex- rocuronium complex were confirmed as allergenic epitopes. PMID: 31619026 [PubMed - as supplied by publisher]
Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research
Conclusions: High EI of ILT may predict the occurrence of type II endoleaks after EVAR of AAA. PMID: 31621439 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
More News: Allergy | Allergy & Immunology | Dermatology | Skin | Thrombosis | von Willebrand Disease