Mechanism proposed for microvascular thrombosis in thrombotic thrombocytopenic purpura

In patients with acquired autoimmune thrombotic thrombocytopenic purpura, elevated plasma levels of human neutrophil proteins 1-3 inhibit proteolytic cleavage of von Willebrand factor by ADAMTS13, Vikram G. Pillai, PhD, of the University of Alabama at Birmingham, and colleagues reported. The...
Source: Skin and Allergy News - Category: Dermatology Source Type: news

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Authors: Hirayama T, Morioka H, Fujiwara H, Iwamoto K, Kiyozuka T, Takeo H, Ikeda K, Kano O Abstract The frequency and risk of embolism by Lambl's excrescences (LEs) remain unclear. We herein report an autopsy case of LEs that caused cardioembolic stroke. A 74-year-old man with colon cancer was hospitalized for ischemic stroke. His D-dimer levels were elevated. Thus, a diagnosis of ischemic stroke with Trousseau syndrome was made. At the autopsy, we found LEs in the aortic valves and thromboembolism of the brain blood vessels. This finding demonstrated that fibrin clots had adhered to the LEs because of coagulation...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Abstract Low preoperative physical function in cancer patients is associated with postoperative complications; however, there have been no reports on the benefits of in-hospital preoperative rehabilitation on preoperative physical function in patients with pancreatic cancer. Therefore, the aim of this study was to quantitatively determine the effects of preoperative in-hospital rehabilitation provided under the supervision of a physiotherapist, on preoperative physical function in patients with pancreatic cancer. The study subjects were 26 patients (15 males, 11 females; age 71.2 ± 8.5 years, range: 51-87 y...
Source: The Tohoku Journal of Experimental Medicine - Category: Research Authors: Tags: Tohoku J Exp Med Source Type: research
Authors: Zhang H, Cao Y, Pei H, Wang H, Ma L, Wang Z, Diao X, Yang Y, Liu N, Wei Y, Li H Abstract Shenmayizhi formula (SMYZF) has been shown to have an effect on vascular dementia (VaD) in previous studies. The aim of this study was to evaluate whether a combination of SMYZF with Ginkgo extract tablets improves mild-to-moderate VaD. In this 12-week, randomized, double-blind, controlled study, we randomly assigned 196 patients with VaD (aged 50-85 years) to either the SMYZF group (n = 98) or the Ginkgo group (n = 98). All patients received Ginkgo extract tablets as a basic treatment, whil...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
CONCLUSION: Fibroblastic sleeve is a frequent (29.9%) but asymptomatic finding in oncological and hematological patients with peripherally inserted central catheter, and-in the vast majority of cases-it occurs within 2 weeks after insertion. If compared to fibroblastic sleeve, asymptomatic catheter-related thrombosis is less frequent (5.51%); symptomatic catheter-related thrombosis is rare (
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Authors: Pinelli F, Balsorano P, Mura B, Pittiruti M Abstract Catheter-related thrombosis represents one of the most common complications following central venous access insertion. Despite the amount of available studies, many aspects surrounding catheter-related thrombosis remain controversial. Thirteen years ago, the Italian Study Group for Long Term Central Venous Access (GAVeCeLT) developed a nationwide Consensus in order to clarify some key aspects on this topic. Despite most of them still remain valid, however, knowledge around catheter-related thrombosis has greatly evolved over the last decade, with a natur...
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Food allergy is an atopic disease that is caused by the immune system targeting harmless food antigens that can result in life-threatening anaphylaxis. As humans and microbes have co-evolved, inevitably commensal microbes have a tremendous impact on our health. As such, the gut with its enormous microbial richness reflects a highly tolerogenic environment at steady state, in which immune cells are educated to react in a well-calibrated manner to food and microbial antigens. Recent evidence indicates that the susceptibility to food allergy is critically linked to microbial dysbiosis and can be transmitted by microbial trans...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Publication date: September 2020Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders, Volume 8, Issue 5Author(s): Ebuzer Aydin, Mehmet Senel Bademci, Cemal Kocaaslan, Ahmet Oztekin, Emine Seyma Denli Yalvac
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Publication date: September 2020Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders, Volume 8, Issue 5Author(s): R.J. de Kleijn, L. Schropp, J. Westerink, G.J. de Borst, B.J. Petri
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Publication date: September 2020Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders, Volume 8, Issue 5Author(s): Sandra Toth, Tanya R. Flohr, Jane Schubart, Amy Knehans, Maria C. Castello, Faisal Aziz
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Publication date: Available online 30 July 2020Source: Journal of Vascular Surgery: Venous and Lymphatic DisordersAuthor(s): Edward S. Cho, Paul H. McClelland, Olivia Cheng, Yuri Kim, James Hu, Michael E. Zenilman, Marcus D'Ayala
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
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