Global Progress On Infertility Has Local Impact

I recently wrote about the world's largest conference on issues of women's health and rights and how infertility has finally made it onto the global women's health agenda. That's a big deal. Although such a development sounds disconnected from making a difference to your own experience in dealing with infertility, the truth is it matters. We often talk about healthcare being local and that's true. You likely choose your fertility specialist and clinic based on recommendations as well as general proximity to where you live. However, advances in infertility research and treatment often come from other countries that unlike the US don't have political or funding restrictions on certain types of medical research that may involve embryos. That means breakthroughs that may make a difference in US infertility research and treatment have come from the United Kingdom, Sweden, and China. For example, new "imported" techniques in the lab will aid our understanding of how embryos develop to help advance our ability to select the best embryos to implant for a pregnancy and healthy baby. This is especially important as most couples would prefer to implant a single embryo to avoid multiple births. New treatments from other countries have also helped us more effectively treat older women and those experiencing repeated miscarriages. These developments - and the dissemination of information to researchers and infertility specialists - don't happen in a vacuum. They occur becaus...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: Available online 15 December 2018Source: Journal of Minimally Invasive GynecologyAuthor(s): Huiying Zhang, Huixia Zhang, Xueqing He, Wenyan Tian, Xueru SongABSTRACTEndometrial polyps are frequently encountered in the uterine cavity of infertile women. There is much debate regarding the treatment of endometrial polyps in patients who are undergoing assisted reproductive technology (ART). A systematic review was performed by searching PubMed, Embase, and the Cochrane Library for retrospective or prospective studies that compared the effect of hysteroscopic resection of polyps with no treatment on pregnancy ...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionsSelection of a single blastocyst based on information derived from time-lapse monitoring can aid embryo selection for SET.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Endometrial polyps are frequently encountered in the uterine cavity of infertile women. There is much debate regarding the treatment of endometrial polyps in patients who are undergoing assisted reproductive technology (ART). A systematic review was performed by searching PubMed, Embase, and the Cochrane Library for retrospective or prospective studies that compared the effect of hysteroscopic resection of polyps with no treatment on pregnancy outcomes of patients who underwent ART. Primary outcomes were clinical pregnancy, live birth, miscarriage, and implantation rate after ART.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: REVIEW ARTICLE Source Type: research
CONCLUSIONS: Despite the significant proportion and recent growth of Catholic health care within the U.S. health care sector, little is known about reproductive health outcomes in these settings and in comparison with other settings. PMID: 30531578 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
ConclusionFCM is widely used to assess cellular populations, but not typically employed for endometrial evaluation. FCM provides a rapid, detailed, and quantitative analysis and reduces inter-observer subjectivity bias. Detailed understanding of the normal endometrial immunophenotype, and associated deviations, may provide insight into the aetiology of infertile patients labelled “unexplained”. Failure despite transfer of high grade, or proven euploid blastocysts, is a difficult problem, and endometrial profiling may help identify research areas to determine potential future therapeutic interventions for this d...
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
Background.Infertility is common after HCT predominantly as a result of the chemoradiotherapy used in conditioning. Patients are increasingly encouraged to store gametes, tissue or embryos before transplant for use after their potentially sterilising treatment. Furthermore, some patients do retain or recover fertility and conceive naturally.Methods:We sent questionnaires to 602 EBMT centers requesting retrospective details of number of pregnancies following either allogeneic or autologous HCT, use of artificial reproductive techniques (ART) and pregnancy outcome for all patients treated between 1995-2015.Results:47 centers...
Source: Blood - Category: Hematology Authors: Tags: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster I Source Type: research
ConclusionPresence of adenomyosis seems to have adverse effects on IVF outcomes in clinical pregnancy rate, live birth rate and miscarriage rate. Screening for adenomyosis might be considered before ART so that the couple has better awareness of the prognosis.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Publication date: Available online 22 October 2018Source: Reproductive BioMedicine OnlineAuthor(s): SpanishInfertility SWOT Group (SISG), MA Checa, J Bellver, E Bosch, JJ Espinós, F Fabregues, J Fontes, J García-Velasco, A RequenaAbstractHysteroscopic septum resection in women with unfavourable reproductive and clinical outcomes has become common practice worldwide to improve reproductive results. No clear evidence on the possible advantages and drawbacks of this procedure has been published. In this opinion paper, based on a SWOT (strengths, weaknesses, opportunities, threats) analysis, the different aspects...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
The objective of this study was to demonstrate a markedly enlarged isthmocele, that resulted in the miscarriage of a 12-week IVF twin pregnancy.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
This study investigated the quality and quantity of eggs and embryos as well as the clinical pregnancy outcome in young infertile women with diminished ovarian reserve (DOR) after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). MATERIAL AND METHODS We retrospectively reviewed records of 4285 infertile women and divided them into 3 groups according to age and ovarian reserve: young women with normal ovarian reserve (n=1695), young women with DOR (n=1121), and older women with DOR (n=1469). RESULTS In young women with DOR, the proportion of high-quality embryos was significantly higher than in older women...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
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