Global Progress On Infertility Has Local Impact
I recently wrote about the world's largest conference on issues of women's health and rights and how infertility has finally made it onto the global women's health agenda. That's a big deal. Although such a development sounds disconnected from making a difference to your own experience in dealing with infertility, the truth is it matters. We often talk about healthcare being local and that's true. You likely choose your fertility specialist and clinic based on recommendations as well as general proximity to where you live. However, advances in infertility research and treatment often come from other countries that unlike the US don't have political or funding restrictions on certain types of medical research that may involve embryos. That means breakthroughs that may make a difference in US infertility research and treatment have come from the United Kingdom, Sweden, and China. For example, new "imported" techniques in the lab will aid our understanding of how embryos develop to help advance our ability to select the best embryos to implant for a pregnancy and healthy baby. This is especially important as most couples would prefer to implant a single embryo to avoid multiple births. New treatments from other countries have also helped us more effectively treat older women and those experiencing repeated miscarriages. These developments - and the dissemination of information to researchers and infertility specialists - don't happen in a vacuum. They occur becaus...
Conclusion Careful consideration of primary ectopic pregnancy data is a valuable tool to predict the potential risk of recurrence in the future.
To compare sperm parameters, serum hormone levels, pregnancy and miscarriage rates between the infertile men with recurrent or persistent varicocele who underwent microsurgical subinguinal redo varicocelectomy or had observation only.
ConclusionsThis prospective case-control study is one of the largest to examine environmental factors, sperm characteristics, sperm DNA fragmentation and chromatin, and chromosome anomalies in spermatozoa in relation to unexplained recurrent pregnancy loss. The originality of our study lies in the comprehensive andrological examination and search for risk factors and fertility history. Further studies are needed to confirm the links between unexplained RPL and a male family history of infertility or miscarriages. The increased sperm aneuploidy observed in unexplained RPL supports a male etiology. These data pave the way fo...
*This blog was first published at DNA Science Blog at Public Library of Science* The spindle apparatus is among the most elegant structures in a cell, quickly self-assembling from microtubules and grabbing and aligning chromosomes so that equal sets separate into the two daughter cells that result from a division. But can spindles in cells held at the brink of division in the suspended animation of the deep freeze at a fertility clinic survive being ripped from their slumber off-protocol, as happened the weekend of March 4 at the Pacific Fertility Clinic in San Francisco and University Hospitals Fe...
Conclusion Findings revealed an improvement in pregnancy rates following hCG administration in FET cycles.
This study presents a summary of the investigations that indicate the key role of stem cell therapy in regeneration and renovation of defective parts.
This study presents a summary of the investigations that indicate the key role of stem cell therapy in regeneration and renovation of defective parts. PMID: 29571018 [PubMed - as supplied by publisher]
Conclusion: Infertile women with TAI treated with ICSI had no increased risk of a first trimester miscarriage compared with women without TAI. PMID: 29546422 [PubMed - as supplied by publisher]
Conclusion Y chromosome microdeletions and chromosomal heteromorphism are not associated with RPL in Northeast China. Some RPL males had structural chromosome anomalies, all of which were reciprocal translocations. We suggest that it may not be necessary to detect Y chromosome microdeletions in RPL males with Yqh±.
Recurrent pregnancy loss (RPL) is defined as the miscarriage of 2 or more clinical pregnancies. The majority of cases remain unexplained after standard evaluations for anti-phospholipid antibody syndrome (APAS), uterine anomalies and parental karyotypes. While ovarian reserve testing is recommended for women with infertility, the role of ovarian reserve testing in the setting of RPL is unknown.