H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis

Epigenetic changes (i.e., chromatin modifications) occur during chondrogenesis and in osteoarthritis (OA). We investigated the effect of H3K27me3 demethylase inhibition on chondrogenesis and assessed its utili...

Source: Arthritis Research and Therapy - July 7, 2016 Category: Rheumatology Authors: Clarence Yapp, Andrew J. Carr, Andrew Price, Udo Oppermann and Sarah J. B. Snelling Source Type: research