Counterfeit adderall containing aceclofenac from internet pharmacies - Gaudiano MC, Borioni A, Antoniella E, Valvo L.

A nontargeted approach based on liquid chromatography equipped with a quadrupole time-of-flight mass detector (LC-MS Q-TOF) joined to nuclear magnetic resonance (NMR) analysis allowed rapid identification and quantification of the anti-inflammatory drug ac...
Source: SafetyLit - Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

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Conclusions: The constantly increasing prevalence of NAFLD in the general population can contribute to a growing role of NAFLD/NASH in HCC epidemiology. Moreover, some particular challenges specific for patients with liver steatosis may impede proper HCC diagnosis, treatment and follow-up. PMID: 31631714 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
In this study, a mouse model of chronic alcoholic hepatitis was established by eight weeks of Lieber-DeCarli liquid diet feeding; and LGG-s, BMMSCs or a combination of the two were used to explore a new therapeutic method for alcoholic liver disease and to study the mechanism. The results showed that the combined LGG-s and BMMSC treatment might have a synergistic effect and could improve the symptoms of alcoholic hepatitis by regulating inflammation, autophagy and lymphocyte subsets through the PI3k/NF-kB and PI3K/mTOR pathways. With the treatment, the autophagy rate accelerated, and alcohol-induced natural killer B (NKB) ...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Conclusions/interpretationThese results indicate thatLight deficiency in HFHCD improves hepatic glucose tolerance, and reduces hepatic inflammation and NAFL. This is accompanied by decreased systemic inflammation and adipose tissue cytokine secretion and by changes in the expression of key genes such asKlf6 andTlr4 involved in NAFLD. These results suggest that therapies to block LIGHT-dependent signalling might be useful to restore hepatic homeostasis and to restrain NAFLD.
Source: Diabetologia - Category: Endocrinology Source Type: research
Publication date: Available online 21 October 2019Source: Food ChemistryAuthor(s): Olaf J. Schelezki, Guillaume Antalick, Katja Šuklje, David W. JefferyAbstractPre-fermentative juice substitution with water or early harvest wine has the potential to produce lower alcohol wines without critically modifying colour or tannin properties and only marginally changing volatile and sensory profiles. Whether this approach is suited to producing lower alcohol wines in the absence of excessive grape ripeness remained to be determined. The current study extends on pre-fermentative approaches to alcohol management under milder g...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 21 October 2019Source: Journal of Molecular StructureAuthor(s): Gemma Leone, Marco Consumi, Simone Pepi, Alessio Pardini, Claudia Bonechi, Gabriella Tamasi, Alessandro Donati, Claudio Rossi, Agnese MagnaniAbstractPoly-vinyl alcohol (PVA) with different molecular weight (27 kDa, 31 kDa, 61 kDa, 125 kDa and 195 kDa) were phosphorylated with trisodium trimetaphosphate (STMP) or sodium hexa-metaphosphate (SHMP) working at pH 10 or 12. Strong chemical hydrogels (G’>G”) were obtained starting from polymers with higher MW (61 kDa, 125 kDa and 195 kDa). Infrared Spe...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: 15 December 2019Source: Journal of Molecular Liquids, Volume 296Author(s): Mahmoud Rahmati, Marjan Jangali, Hossein RezaeiAbstractThe conductivity and diffusion of hydronium ions at 298 K in PVA (Polyvinyl alcohol), PBI (Polybenzimidazole) and SPEEK (Sulfonated polyether ether ketone) as known membranes of PEMFCs have been investigated using molecular dynamics simulation method throughout this work. The simulation results show that the diffusion of hydronium ions in these polymer membranes depends on the polymer structure and water concentration in the membrane. On the other hand, RDF analysis results a...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
In this study, the gel bead was characterized using FTIR, XPS, SEM, EDS, and 13C NMR. The experimental data shows that there is a strong correlation between adsorption capacity. The adsorption data fitted well with the Freundlich isotherm model and the pseudo-second-order model. The results of thermodynamics show that the adsorption process is spontaneous, endothermic, and increases entropy. The maximum adsorption capacity for DS was calculated as 493.81 mg/g at pH 5 (308 K). The adsorbent still exhibited excellent adsorption capacity after recycling five times, showing it has excellent potential for practical applicat...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: Available online 21 October 2019Source: Microchemical JournalAuthor(s): Binbin Guan, Zhaoli Xue, Quansheng Chen, Hao Lin, Jiewen ZhaoAbstractThis work presents a real-time ethanol content measurement method during the solid-state fermentation of “Zhenjiang” Aromatic vinegar. 5, 10, 15, 20-Tetraphenyl-21H, 23H-porphine zinc (ZnTPP) which was sensitive to ethanol was employed to capture VOC from semi-solid state vinegar during fermentation. Various self-assembled nanostructures of ZnTPP based was be synthesized, while the effect of aging time and the pH on the morphology of nanoporphyrin has bee...
Source: Microchemical Journal - Category: Chemistry Source Type: research
CrystEngComm, 2019, Accepted Manuscript DOI: 10.1039/C9CE00965E, PaperJinyao Chen, Wenming Zhu, Weijie Ji, Bin Zhu, Chunyang Guo, Ming-Hui Qi, Guo-Bin Ren During a comprehensive structure and stability study on the hydrates and alcohol solvates of pharmaceutical molecule ginsenoside compound K (20-O- β-glucopyranosyl-20(S)-protopanaxadiol, GCK), the crystal structure of hemihydrate (HH), ethanol solvate (SEt)... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - CrystEngComm latest articles - Category: Chemistry Authors: Source Type: research
Condition:   Alcohol Use Disorder Intervention:   Device: transcranial direct current stimulation Sponsors:   Shanghai Mental Health Center;   Wuhan Union Hospital, China Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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