Unique use of heart-lung machine saves heart attack victim at UCLA emergency room
James Manzi is lucky to be alive. When the 79-year-old Brentwood, Calif., resident arrived at Ronald Reagan UCLA Medical Center's emergency room in full cardiac arrest, the medical team tried everything to stabilize him, including shocking his heart 29 times with a defibrillator in an attempt to restore a normal rhythm. Often, patients whose heart attacks are as severe as Manzi's don't survive. Only one out of every 10 people who suffer cardiac arrest outside the hospital lives through the ordeal. As the team worked, UCLA emergency medicine physician Dr. Eric Savitsky monitored Manzi's diminishing response to their resuscitative efforts using a combination of bedside ultrasound of the heart and clinical indicators. This led to an emergeny request for a rarely used but potentially lifesaving technology known as extracorporeal membrane oxygenation, or ECMO. ECMO involves the use of a sophisticated pump that takes over the functions of the heart and lungs, essentially breathing for the patient by pumping oxygenated blood to vital organs so the lungs can rest. This helps reduce stress on the heart. The device is traditionally used to support adults in cardiac failure waiting for a heart transplant and to help protect the delicate respiratory systems of infants born prematurely. Fortunately, it worked in Manzi's case too. His heart stabilized, allowing the cardiac team to transport him to the cardiac catheterization lab, where he underwent...
Publication date: Available online 22 October 2018Source: The Egyptian Heart JournalAuthor(s): Siva Subramaniyan, Neeraj Pandit, Ranjit Kumar Nath, Ajay Raj, Athar Kamal, Deepankar VatsaAbstractBackgroundIt is well established fact that acute coronary occlusion leads to diastolic dysfunction, followed by systolic dysfunction when myonecrosis occur. It is also proven that primary percutaneous coronary intervention (PPCI) is an excellent therapy for ST elevation myocardial infarction (STEMI) to improve outcomes. However there is a paucity of information on efficacy of PPCI in improving diastolic function. Evaluation of the r...
(MedPage Today) -- Heart attack tied to " more prolonged risk of stroke than we have thought
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Condition: Myocardial Infarction Interventions: Drug: Ramipril; Drug: Firibastat Sponsor: Quantum Genomics SA Not yet recruiting
We describe a modified transatrial approach through the left atrium for basal-inferior VSD. After left atriotomy, mitral valve is detached from the annulus to expose the defect, which is closed with a pericardial patch. Two patients were operated by this method. In both cases veno-arterial extracorporeal membrane oxygenation with a ventricular vent was utilised to unload the left ventricle. Echocardiography revealed no residual shunt in both cases.
We present a case of myocardial infarction and ventricular rupture in a young individual with limited underlying coronary disease and habitual cocaine use. The role of each is discussed.
AbstractThe EUROASPIRE surveys (EUROpean Action on Secondary Prevention through Intervention to Reduce Events) demonstrated that most European coronary patients fail to achieve lifestyle, risk factor and therapeutic targets. Here we report on the 2-year incidence of hard cardiovascular (CV) endpoints in the EUROASPIRE IV cohort. EUROASPIRE IV (2012 –2013) was a large cross-sectional study undertaken at 78 centres from selected geographical areas in 24 European countries. Patients were interviewed and examined at least 6 months following hospitalization for a coronary event or procedure. Fatal and non-fatal CV ev...
Patients are more likely to benefit from antihypertensive therapy if they have good oral health Related items fromOnMedica Hypertension raises risk of mitral regurgitation Blood pressure measurement Follow clinical guidance to measure BP in both arms Too few women take part in many CVD clinical trials Heart attack protocol eliminates gender gap in outcome
ConclusionsA single medium dose of EPO could have a favorable effect on CMD and LA remodeling in the chronic phase of anterior AMI.Trial RegistrationThe institutional ethics committee of Wakayama Medical University, identifier, 1125.
AbstractAlthough cell therapy improves cardiac function after myocardial infarction, highly variable results and limited understanding of the underlying mechanisms preclude its clinical translation. Because many heart failure patients are diabetic, we examined how diabetic conditions affect the characteristics of cardiac mesenchymal cells (CMC) and their ability to promote myocardial repair in mice. To examine how diabetes affects CMC function, we isolated CMCs from non-diabetic C57BL/6J (CMCWT) or diabetic B6.BKS(D)-Leprdb/J (CMCdb/db) mice. When CMCs were grown in 17.5 mM glucose, CMCdb/db cells showed> ...
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