Abstracts from the 5th International Conference for Healthcare and Medical Students (ICHAMS)

Table of contents O1: Assessing the protective effect of dexrazoxane against doxorubicin-induced toxicity in HL-1 cardiomyocytes Yvonne Sweeney, Hugh O’Neill, Garry Duffy O2: Role of KCNQ1 in epithelial barrier repair Daniel Creegan, Viviana Bustos, Brian J. Harvey O3: The suitability of non-small cell lung cancer cytology preparations for the analysis of anaplastic lymphoma kinase gene rearrangements Alexander Dalphy, Anthony O’Grady, Elaine Kay O4: Penetrating keratoplasty and descemet’s stripping automated endothelial keratoplasty may lead to deterioration in glaucoma management Katarzyna Samelska, Justyna Izdebska, Anna Kurowska O5: The effect of Resolvin D1 on normal and cystic fibrosis human bronchial epithelium Rena Al-Zubaidy, Magdalena Mroz, Brian Harvey O6: Validity of clinical assessment compared with plantar fascia thickness on ultrasound for plantar fasciitis: a cross-sectional study Ryan Fagan, Helen French, Vanessa Cuddy, Jennifer Ashton, Michelle Clarke P1: Undergraduate medical research in Gulf Cooperation Council (GCC) countries: A descriptive study of students’ views Zaid Sayedalamin, Mukhtiar Baig, Osama Almutairi, Hassan Allam, Taher F. Halawa, Hazem M. Atta P2: Positive fluid balance as a prognostic factor in children with sepsis during first 3 hours of resuscitation in intensiv...
Source: BMC Proceedings - Category: Biomedical Science Source Type: research

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In this study, 5% w/v SMP dispersion was acidified to pH 2.4–3.0 using citric acid and heated at different conditions. Lowering pH resulted in dissolution of colloidal calcium phosphate from casein micelles, corresponding to lowered turbidity and reduced hydrodynamic diameter of dispersions. When heated for 10 min at different temperatures, 70 °C was the most effective to produce transparent dispersions; whereas a shorter heating time between 2 and 60 min was desired at 90 °C. The decreased turbidity after heating was attributed to weakened hydrophobic interaction between casein molecules based on f...
Source: Food Hydrocolloids - Category: Food Science Source Type: research
Publication date: Available online 14 October 2019Source: Food ChemistryAuthor(s): Jianghao Sun, Craig S. Charron, Janet A. Novotny, Bing Peng, Liangli Yu, Pei ChenAbstractBroccoli is a popular brassica vegetable and its consumption may decrease the occurrence of cancer in certain populations. To gain insight into the metabolites that may induce physiological responses to broccoli intake, a non-targeted metabolomic approach and a targeted approach for analysis of glucosinolate metabolites were developed using high resolution accurate mass spectrometry. A human study was conducted in which 6 subjects consumed a single meal ...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 13 October 2019Source: Journal of Molecular LiquidsAuthor(s): Hany M.Abd El-Lateef, Zeinab A. Abdallah, Mohamed S.Mohamed AhmedAbstractEthyl 2-(1,2,3,6-tetrahydro-6-oxo-2-thioxopyrimidin-4-yl)ethanoate (EOTPE) was synthesized by a facile and cost-effective method. The structure confirmation of the synthesized EOTPE was performed by different spectroscopic methods. The corrosion inhibition action of EOTPE in pickling acids (1.0 N HCl and1.0 N H2SO4) at different temperatures (30–60 °C) was tested by various surface and corrosion methods, including open circuit potential (...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: November 2019Source: Fish &Shellfish Immunology, Volume 94Author(s): Elumalai Preetham, Abdul Salam Rubeena, Baskaralingam Vaseeharan, Mukesh Kumar Chaurasia, Jesu Arockiaraj, Rolf Erik OlsenAbstractThe study is carried out to understand the antimicrobial and immunological response of a potential immune molecule lectin, MmLec isolated from haemolymph of Speckled shrimp, Metapenaeus monoceros. MmLec was purified using mannose coupled Sepharose CL-4B affinity chromatography, which was further subjected on SDS-PAGE to ascertain the distribution of their molecular weight. Sugar binding specificity assay w...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 13 October 2019Source: Advances in Biological RegulationAuthor(s): Veronica Balatti, Carlo M. CroceAbstractWe established that loss of miR-15a/16–1 genes on chromosome 13q14 is the most common alteration in Chronic Lymphocytic Leukemia (CLL) and that miR-15/16 are crucial negative regulator of BCL-2, an antiapoptotic gene overexpressed in most CLLs and in many other malignancies. We have also shown that miR-15/16 target ROR1, a cell surface receptor for Wnt5a which can enhance growth/survival of CLL cells. Interestingly, ROR1 is expressed by many cancers, but not by normal adult tis...
Source: Advances in Biological Regulation - Category: Biology Source Type: research
The purpose of this study was to evaluate the relationship between the circadian profile of the vasorelaxing substances calcitonin gene-related peptide (CGRP) and epoxyeicosatrienoic acids (EETs) and the vasconstrictive agent endothelin-1 (ET1) and the daily rhythms of cardiac hemodynamic indices (CHI) and baroreflex (BRS) in Wistar rats with 1 kidney-1 clip model of arterial hypertension (1K-1C AH). The animals were divided into 3 groups: I- sham-operated (SO), II- 4-week and III- 8-week 1K-1C AH rats. Plasma concentration of ET1, CGRP and EET ’s were investigated every 4 h. In conscious freely moving 1K-1C AH rats ...
Source: Journal of Circadian Rhythms - Category: Biology Source Type: research
Publication date: 1 December 2019Source: Colloids and Surfaces B: Biointerfaces, Volume 184Author(s): Maosheng Xu, Kunsong Zhang, Yubing Liu, Jie Wang, Ke Wang, Yuanqing ZhangAbstractThe treatment of cancer has always been a worldwide problem. The combination of chemotherapy and other therapies would be a promising therapy strategy. Photothermal therapy (PTT) does not cause serious side effects and has dual control of time and space, which was considered to be a good method for combination with chemotherapy. Here, we modified multifunctional nanosheets based on in-situ gold nanoparticles (Au NPs) grown molybdenum disulfide...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: Available online 14 October 2019Source: Biochemical Engineering JournalAuthor(s): Jinfeng Li, Guowei Shang, Yisheng Wang, Xiuli Wang, Yuanyuan Ji, Yuebai LiAbstractCalcitonin gene-related peptide (CGRP) promotes proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), which influence bone regeneration and reconstruction. We previously established CGRP-modified BMSCs that express the CGRP gene and demonstrated that this elevated CGRP expression promotes osteogenic differentiation of BMSCs. The current study investigated the therapeutic effects of CGRP-modified BMSCs combi...
Source: Biochemical Engineering Journal - Category: Biochemistry Source Type: research
Publication date: Available online 13 October 2019Source: Sensors and Actuators B: ChemicalAuthor(s): Zakie Anajafi, Mahmoud Naseri, G. NeriAbstractIn this paper, the synthesis, characterization and sensing properties of SmFeO3/ZnO nanocomposite synthesized by the thermal treatment method, is reported. The morphological and microstructural characteristics of the synthesized composite nanopowders and single SmFeO3 and ZnO components, were analyzed by Scanning Electron Microscopy-Electron Dispersive X-ray (SEM-EDX), X-ray diffraction (XRD), Fourier Transform-Infrared (FT-IR) spectroscopy and Photoluminscence (PL). Characteri...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Publication date: Available online 13 October 2019Source: Sensors and Actuators B: ChemicalAuthor(s): Chenyu Yao, Limin Xiao, Shoufei Gao, Yingying Wang, Pu Wang, Ruifeng Kan, Wei Jin, Wei RenAbstractWe demonstrated the sensitive CO detection in a novel hollow-core negative curvature fiber (HC-NCF) with infrared laser absorption at 2.3 µm. The HC-NCF consists of a single ring of eight nontouching silica capillaries around the air core, providing a single-mode light delivery of the 2.3-µm distributed feedback laser. A high coupling efficiency of 90% was achieved with the aid of optimal free-space coupling...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
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