[Multiparametric and molecular imaging of breast tumors with MRI and PET/MRI].

[Multiparametric and molecular imaging of breast tumors with MRI and PET/MRI].
Radiologe. 2016 Jun 30;
Authors: Pinker K, Marino MA, Dr Meyer-Baese A, Helbich TH
Abstract
CLINICAL/METHODICAL ISSUE: Magnetic resonance imaging (MRI) of the breast is an indispensable tool in breast imaging for many indications. Several functional parameters with MRI and positron emission tomography (PET) have been assessed for imaging of breast tumors and their combined application is defined as multiparametric imaging. Available data suggest that multiparametric imaging using different functional MRI and PET parameters can provide detailed information about the hallmarks of cancer and may provide additional specificity.
STANDARD RADIOLOGICAL METHODS: Multiparametric and molecular imaging of the breast comprises established MRI parameters, such as dynamic contrast-enhanced MRI, diffusion-weighted imaging (DWI), MR proton spectroscopy ((1)H-MRSI) as well as combinations of radiological and MRI techniques (e. g. PET/CT and PET/MRI) using radiotracers, such as fluorodeoxyglucose (FDG).
METHODICAL INNOVATIONS: Multiparametric and molecular imaging of the breast can be performed at different field-strengths (range 1.5-7 T). Emerging parameters comprise novel promising techniques, such as sodium imaging ((23)Na MRI), phosphorus spectroscopy ((31)P-MRSI), chemical exchange saturation transfer (CEST) imaging, blood oxygen level-dependent (BOL...

Source: Der Radiologe - June 29, 2016 Category: Radiology Authors: Pinker K, Marino MA, Dr Meyer-Baese A, Helbich TH Tags: Radiologe Source Type: research