[PERSPECTIVES] Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC

This article will summarize the history of LpxC as a drug target and the parallel history of research on LpxC biology. Both academic and industrial researchers have used LpxC inhibitors as tool compounds, leading to increased understanding of the differing mechanisms for regulation of LPS synthesis in Escherichia coli and Pseudomonas aeruginosa.
Source: Cold Spring Harbor perspectives in medicine - Category: Research Authors: Tags: Antibiotics and Antibiotic Resistance PERSPECTIVES Source Type: research