Natural metabolite can suppress inflammation

(ITMO University) An international research team has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages -- specific immune cells. The substance known as itaconate is released in large quantities by macrophages themselves and according to the scientists, acts as an antioxidant and anti-inflammatory agent. These properties make itaconate promising for the treatment of such pathologies as cardiac ischemia, metabolic disorders and autoimmune diseases which may be associated with excessive inflammation or oxidative stress.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news