Does Delayed Graft Function Still Herald a Poorer Outcome in Kidney Transplantation?

Abstract Delayed graft function (DGF), or post-operative acute kidney injury leading to the need for dialysis within the first week after kidney transplantation, most commonly occurs in the setting of donor kidney recovery and the ischemia–reperfusion injury associated with the transplantation process. Despite advances in immunosuppressive regimens and medical management of kidney transplant recipients, the short- and long-term sequelae of DGF continue to be important determinants of kidney allograft prognosis. In this review, we will highlight the following areas as it relates to DGF: definition, pathophysiology, epidemiology, graft and patient outcomes, prediction, and some points on management.
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research