Primary ovarian insufficiency associated with autosomal abnormalities: from chromosome to genome-wide and beyond

Conclusions: The considerably complex process of POI is still not well understood. Further research is needed for gene functional validation studies to confirm the contribution of genes in POI, or additional genome-wide association studies using novel clustered regularly interspaced short palindromic repeat/Cas9 technique might make these mechanisms more comprehensible.
Source: Menopause - Category: OBGYN Tags: Review Article Source Type: research