BLM CO, Alpine Native Plants Material Development and Conservation.

Funding Opportunity ID: 285313 Opportunity Number: L16AS00211 Opportunity Title: BLM CO, Alpine Native Plants Material Development and Conservation.Opportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: Cooperative AgreementCategory of Funding Activity: Natural ResourcesCategory Explanation: CFDA Number(s): 15.231Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Additional Information on Eligibility: Agency Code: DOI-BLMAgency Name: Department of the InteriorBureau of Land ManagementPosted Date: Jun 22, 2016Close Date: Aug 19, 2016Last Updated Date: Jun 22, 2016Award Ceiling: $50,000Award Floor: $2,500Estimated Total Program Funding: $50,000Expected Number of Awards: 1Description: This project will address the following objectives from the National Seed Strategy:Action 2.2.1 Conduct seed germination studies and develop seed testing protocols for key restoration species;Action 2.2.2 Develop storage guidelines for restoration species to improve maintenance of seed viability;Action 2.2.3 Develop species-specific protocols for seed and seedling production practices that maintain genetic diversity;To further the conservation and/or recovery of Penstemon debilis by investigating techniques for growing the plant and understand how it might be transplanted into its native habitat.Version...
Source: Grants.gov - Category: Research Tags: Natural Resources Source Type: funding

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This article discusses the historic context of HDM-ASCT, the modern role of HDM-ASCT given the availability of highly sensitive MRD testing, and the likely future of quadruplet treatment. In summary, patients who attain deep responses using IMiD- and PI-based regimens may not require early HDM-ASCT. A delayed approach to this treatment is acceptable, and might be preferred by patients. PMID: 31730582 [PubMed - in process]
Source: Clinical Advances in Hematology and Oncology - Category: Cancer & Oncology Tags: Clin Adv Hematol Oncol Source Type: research
The association between trough blood concentration and systemic exposure of tacrolimus: Comparison between once-daily (Advagraf®) and twice-daily (Prograf®) formulation in de novo kidney transplant recipients. Drug Metab Pharmacokinet. 2019 Oct 21;: Authors: Sukkha S, Chindavijak B, Nosoongnoen W, Phakdeekitchareon B, Kitiyakara C, Sumethkul V Abstract Available data of early conversion from twice-daily tacrolimus (TAC-BID) to once-daily tacrolimus (TAC-OD) in de novo kidney transplant (KT) recipients are limited. We conducted a prospective study of early conversion to TAC-OD in de novo KT reci...
Source: Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Tags: Drug Metab Pharmacokinet Source Type: research
Abstract Mesenchymal Stem Cells (MSCs) represent a heterogeneous group of self-renewal, multipotent non-hematopoietic stem cells, which display profound immunomodulatory functions and promising therapeutic effects. Autoimmune diseases, which result from an aberrant immune response to selfantigens, can be detrimental to nearly all body tissues. With the advance in developing a novel treatment, including biological agents, it is still impossible to cure autoimmune disorders. Recent studies demonstrate the remarkable therapeutic effectiveness of MSCs towards a wide array of autoimmune diseases. In this review, the im...
Source: Current Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Curr Stem Cell Res Ther Source Type: research
Publication date: Available online 16 November 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Fabianne Carlesse, Liane Esteves Daudt, Adriana Seber, Álvaro Pimenta Dutra, Analy Salles de Azevedo Melo, Belinda Simões, Carla Macedo, Carmem Bonfimi, Eliana Benites, Lauro Gregianin, Marjorie Vieira Batista, Marcelo Abramczyk, Vivian Tostes, Henrique Lederman, Maria Lúcia de Martino Lee, Sandra Logetto, Cláudio Galvão, Arnaldo Lopes ColomboAbstractIn the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infec...
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
Biliary atresia (BA) is a fatal condition resulting in the lack of effective biliary drainage leading invariably to liver failure and cirrhosis within a year, and it is often lethal within a few months in the absence of corrective surgery or liver transplantation. In fact, BA is the most common indication for pediatric liver transplantation. Herein, we present a rare case of unexpected infant death due to BA diagnosed only postmortem in a context of child neglect and carelessness on the part of the parents. It emerged from the clinical history that after a few months, the parents no longer took their daughter to any medic...
Source: The American Journal of Forensic Medicine and Pathology - Category: Forensic Medicine Tags: Original Articles Source Type: research
Contributor : Juan R Alvarez-DominguezSeries Type : Methylation profiling by high throughput sequencingOrganism : Homo sapiensStem cell-derived tissues could transform disease research and therapy, yet most methods generate functionally immature products. We investigate how human stem cells differentiate into pancreatic islets in vitro by profiling DNA methylation, chromatin accessibility, and histone modification changes. We find that enhancer potential is reset upon lineage commitment, and show how pervasive epigenetic priming steers endocrine cell fates. Modeling islet differentiation and maturation regulatory circuits ...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by high throughput sequencing Homo sapiens Source Type: research
Publication date: Available online 14 November 2019Source: Fish &Shellfish ImmunologyAuthor(s): Chengzhang He, Ruijuan Hao, Yuewen Deng, Chuangye Yang, Xiaodong DuAbstractThe pearl oyster, Pinctada fucata martensii, produces high-quality pearls. During pearl production, excess immune and inflammatory response after transplantation will lead to nucleus rejection, pearl sac formation failure, and death of the host pearl oyster. The hemocyte transcriptome and fatty acid (FA) contents in the adductor muscle before and after transplantation were analyzed to investigate the response of pearl oyster P. f. martensii to allogra...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 14 November 2019Source: Medicina Intensiva (English Edition)Author(s): J.J. Egea-Guerrero, L. Martín-Villén, Z. Ruiz de Azúa-López, F. Maroto Monserrat, J.A. Sanchez-Román, F. Cabeza-Cabeza
Source: Medicina Intensiva - Category: Intensive Care Source Type: research
Contributor : Juan R Alvarez-DominguezSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensStem cell-derived tissues could transform disease research and therapy, yet most methods generate functionally immature products. We investigate how human stem cells differentiate into pancreatic islets in vitro by profiling DNA methylation, chromatin accessibility, and histone modification changes. We find that enhancer potential is reset upon lineage commitment, and show how pervasive epigenetic priming steers endocrine cell fates. Modeling islet differentiation and maturation regulat...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research
Contributor : Juan R Alvarez-DominguezSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensStem cell-derived tissues could transform disease research and therapy, yet most methods generate functionally immature products. We investigate how human stem cells differentiate into pancreatic islets in vitro by profiling DNA methylation, chromatin accessibility, and histone modification changes. We find that enhancer potential is reset upon lineage commitment, and show how pervasive epigenetic priming steers endocrine cell fates. Modeling islet differentiation and maturation regulat...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research
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