Imaging Chemokine Function in Disease

Immunology Interest Group Dr. Luster studied medicine at Cornell University Medical College and obtained a Ph.D. degree under mentorship of Drs. Jeffrey Ravetch and Zanvil Cohn at the Rockefeller University. As a graduate student, he discovered and characterized the IFN-gamma-inducible protein 10 (IP-10/CXCL10) (Nature 1985; 315:672-676)! He completed residency and a clinical fellowship in medicine and infectious diseases at Massachusetts General Hospital and post-doctoral training in the laboratory of Dr. Philip Leder at Harvard Medical School. In 1994, he joined the faculty of Harvard Medical School and Massachusetts General Hospital and is now a Persis, Cyrus and Marlow B. Harrison Professor Medicine and a Director of Center for Immunology and Inflammatory Diseases at Massachusetts General Hospital. Dr. Luster leads an extremely productive basic/translational science immunology research program. His laboratory focuses on understanding the role of chemokines and lipid chemoattractants and their receptors in controlling the trafficking of leukocytes in vivo. His laboratory discovered several key members of the chemokine gene family (Eotaxin, MCP-4, MCP-5) and developed numerous gene-targeted, transgenic and chemokine reporter mouse strains that have been instrumental in determining the biological activities of chemokines and their role in the pathogenesis of HIV and malaria infections as well as in the pathophysiology of allergic and autoimmune diseases. This is going to be...
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