The H19 long noncoding RNA is a novel negative regulator of cardiomyocyte hypertrophy

Conclusion
These findings reveal a novel function of H19-miR-675 axis targeting CaMKII as a negative regulator of cardiac hypertrophy, suggesting its potential therapeutic role in cardiac diseases.

Source: Cardiovascular Research - June 14, 2016 Category: Cardiology Authors: Liu, L., An, X., Li, Z., Song, Y., Li, L., Zuo, S., Liu, N., Yang, G., Wang, H., Cheng, X., Zhang, Y., Yang, X., Wang, J. Tags: Cardiac biology and remodelling Source Type: research