Haemodynamic unloading reverses occlusive vascular lesions in severe pulmonary hypertension

Conclusion Our results indicate that haemodynamic stress is prerequisite to the development and progression of occlusive neointimal lesions in this rat model of severe pulmonary hypertension. We conclude that perivascular inflammation and occlusive neointimal arteriopathy are driven by haemodynamic stress.
Source: Cardiovascular Research - Category: Cardiology Authors: Tags: Integrative physiology and pathophysiology Source Type: research