Better Outcomes for Patients will Provide Better Business Outcomes

It will not have escaped your attention that ‘patient centricity’ has become something of a catchphrase in the last couple of years: mission statements and company announcements are full of it. Cynics have yet to be convinced, but some believers in pharma are working to win them over. John McCarthy, VP Global Commercial Excellence at AstraZeneca, thinks he has the tools to make the idea something more concrete. The international team he leads has a daunting remit: to build and deliver capabilities to drive commercial success, transform the healthcare experience and improve the lives of millions of patients. Measuring the journey In short, he is leading the charge to make AstraZeneca a patient-centric organization. To know you are achieving this broad and ambitious set of aims requires a laser-like focus on outcomes, and McCarthy believes it is vital to build in measurement from the start. However, there may be a limit to the usefulness of traditional KPIs in this environment. “There are many ways to measure along this journey,” McCarthy says. “We’re probably not measuring patient centricity at a corporate level just yet, but if you’re doing journey mapping and understand the problems, that is probably a measure. KPIs too often bring you back to the business outcome only.” Instead, he suggests, you need to look for evidence that you are solving a problem for patients. The $64 million question which follows on from this – an...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news

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In this study, we aimed to investigate the incidence of Dientamoeba fragilis with different diagnostic methods in patients with gastrointestinal symptoms and determine the sensitivity and specificity of existing diagnostic methods. Fecal samples collected from 101 patients with gastrointestinal complaints (especially upper abdominal pain, abdominal and pelvic pain, nausea and vomiting, gastroenteritis and colitis, unexplained fever and diarrhea) and 20 control cases from various clinics were included in the study. Samples were first examined with native-Lugol (N-L) method and cultured in Robinson medium. All 121 stool and ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
CONCLUSION: Renal diseases and some of the main related diseases corresponded to 12.97% of the expenses in the triennium 2013-2015, and RRT to more than 5% of the SUS expenses with medium and high complexity healthcare. Such high expenses determine great concerns on the future maintenance of treatment for stage-5 CKD in Brazil and countries in similar or worse conditions of development. PMID: 29927463 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
CONCLUSION: There was a significant increase in the number of transplants, with evolution in graft survival, despite the worsening in the profiles of recipients and donors. PMID: 29927459 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
CONCLUSION: This analysis confirmed that in this population, infection is the leading cause of mortality over the first 5 years after kidney transplantation. Several demographic and socioeconomic risk factors were associated with death, most of which are not readily modifiable. PMID: 29927458 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Abstract Platelets are essential for clotting in the blood and maintenance of normal hemostasis. Under pathologic conditions such as atherosclerosis, vascular injury often results in hyperactive platelet activation, resulting in occlusive thrombus formation, myocardial infarction, and stroke. Recent work in the field has elucidated a number of platelet functions unique from that of maintaining hemostasis, including regulation of tumor growth and metastasis, inflammation, infection, and immune response. Traditional therapeutic targets for inhibiting platelet activation have primarily been limited to cyclooxygenase-...
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Tags: Pharmacol Rev Source Type: research
CONCLUSIONS: Pleasure at work for the studied teams was associated with freedom of expression, achievement, and professional recognition, and pain was related to professional exhaustion and work overload. PMID: 29933414 [PubMed - in process]
Source: Revista gaucha de enfermagem EENFUFRGS - Category: Nursing Tags: Rev Gaucha Enferm Source Type: research
In this study we demonstrate the use of clustered regularly interspaced short palindromic repeats (CRISPR)-based epigenome editing to alter cell response to inflammatory environments by repressing inflammatory cytokine cell receptors, specifically TNFR1 and IL1R1. This has applications for many inflammatory-driven diseases. It could be applied for arthritis or to therapeutic cells that are being delivered to inflammatory environments that need to be protected from inflammation." In chronic back pain, for example, slipped or herniated discs are a result of damaged tissue when inflammation causes cells to create ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Editor’s Note: This essay contains excerpts from Extreme Measures: Finding a Better Path to the End of Life, coming February 21st, 2017 from Penguin-Random House. A few years ago, while at a family get-together, I sat across from a retired hospice social worker named Terry. I am a physician whose practice alternates between attending on the wards of an inner-city intensive care unit and serving as a consultant on the hospital’s palliative care team. I didn’t set out to practice this uncommon combination of medical specialties. I started out totally dedicated to using the miraculous technologies in my crit...
Source: Health Affairs Blog - Category: Health Management Authors: Tags: End of Life & Serious Illness Health Professionals Hospitals 30-day mortality statistic advance directive Palliative Care Source Type: blogs
I am in a perpetual abusive relationship with hypochondria; I desperately want to get away from it, but somehow it controls my brain. I've had hypochondriac tendencies (more officially known as "illness anxiety disorder") for as long as I can remember. I'm not sure who or what to blame and the source of the disorder is irrelevant; it's the cure I'm after. Hypothesis theories for my hypochondria: Throughout my childhood, my mother perpetually complained of a bad heart and threatened to faint, falling back on her stash of smelling salts in her purse. The best birthday present I ever got was the Merck Medical Ma...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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